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\u30a4\u30f3\u30bf\u30fc\u30ed\u30a4\u30ad\u30f38\u306f\u708e\u75c7\u6027\u306e\u30b5\u30a4\u30c8\u30ab\u30a4\u30f3\u3067\u3042\u308b\u3001\u305d\u3057\u3066\u3001\u30a2\u30b9\u30d4\u30ea\u30f3\u306f\u6297\u708e\u75c7\u5264\u3067\u3042\u308b\u3002\u5358\u7d14\u306a\u85ac\u3067\u3042\u308b\u30a2\u30b9\u30d4\u30ea\u30f3\u306f\u85ac\u5c40\u3067\u8cb7\u3046\u3053\u3068\u3082\u3067\u304d\u308b\u75db\u307f\u6b62\u3081\u3067\u3042\u308b\u3002\u65b0\u3057\u304f\u9ad8\u4fa1\u306a\u85ac\u3060\u3051\u3067\u306f\u306a\u304f\u3001\u5b89\u4fa1\u3067\u60a3\u8005\u3055\u3093\u306e\u8ca0\u62c5\u3082\u5c11\u306a\u3044\u85ac\u3092\u4f7f\u3063\u3066\u3044\u304f\u3079\u304d\u3060\u308d\u3046<\/p>\n
\u30a2\u30b9\u30d4\u30ea\u30f3\u306f\u524d\u7acb\u817a\u30ac\u30f3\u306e\u7537\u6027\u304c\u3088\u308a\u9577\u304f\u751f\u304d\u308b\u306e\u3092\u63f4\u52a9\u3059\u308b\u53ef\u80fd\u6027\u304c\u3042\u308b\u3068\u3001\u7814\u7a76\u304c\u793a\u5506\u3059\u308b
\nScienceDaily\uff082012\u5e748\u670828\u65e5\uff09\uff0d\u524d\u7acb\u817a\u30ac\u30f3\u306e\u6cbb\u7642\u3092\u53d7\u3051\u305fMen\u306f\u3001\u624b\u8853\u307e\u305f\u306f\u653e\u5c04\u7dda\u3067\u3001\u5b9a\u671f\u7684\u306b\u30a2\u30b9\u30d4\u30ea\u30f3\u3092\u670d\u7528\u3059\u308b\u3053\u3068\u304b\u3089\u5229\u76ca\u3092\u5f97\u308b\u3053\u3068\u304c\u3067\u304d\u305f\u3068\u3001UT\u30b5\u30a6\u30b9\u30a6\u30a7\u30b9\u30bf\u30f3\u533b\u7642\u30bb\u30f3\u30bf\u30fc\u3067\u7814\u7a76\u8005\u3092\u542b\u3080\u65b0\u3057\u3044\u8abf\u67fb\u306b\u306f\u3042\u308b\u3002
\n\u30a2\u30b9\u30d4\u30ea\u30f3\u3092\u670d\u7528\u3059\u308b\u3053\u3068\u306f\u3001Clinical Oncology\u30b8\u30e3\u30fc\u30ca\u30eb\u306e8\u670828\u65e5\u306e\u53f7\u3067\u767a\u8868\u3055\u308c\u308b\u591a\u65bd\u8a2d\u6cbb\u9a13\u306b\u3088\u3063\u3066\u3001\u7279\u306b\u5371\u967a\u6027\u304c\u9ad8\u3044\u75be\u60a3\u306e\u7537\u6027\u3067\u3001\u524d\u7acb\u817a\u30ac\u30f3\u304b\u3089\u3001\u4f4e\u3044\u6b7b\u4ea1\u30ea\u30b9\u30af\u3068\u95a2\u4fc2\u3057\u3066\u3044\u308b\u3002\u30b1\u30d3\u30f3\u30fb\u30c1\u30e7\u30a6\u535a\u58eb\uff08\u30b5\u30a6\u30b9\u30a6\u30a7\u30b9\u30bf\u30f3UT\u306e\u653e\u5c04\u7dda\u816b\u760d\u5b66\u306e\u30a2\u30b7\u30b9\u30bf\u30f3\u30c8\u6559\u6388\uff09\u306f\u3001\u65b0\u805e\u306e\u521d\u306e\u8457\u8005\u3067\u3042\u308b\u3002
\n\u524d\u81e8\u5e8a\u7814\u7a76\u306f\u30a2\u30b9\u30d4\u30ea\u30f3\u3068\u4ed6\u306e\u8840\u6db2\u51dd\u56fa\u306e\u963b\u6b62\u85ac\u7269\u304c\u764c\u6210\u9577\u3068\u8ee2\u79fb\u3092\u963b\u5bb3\u3059\u308b\u53ef\u80fd\u6027\u304c\u3042\u308b\u3053\u3068\u3092\u793a\u3057\u305f\u3001\u3057\u304b\u3057\u3001\u81e8\u5e8a\u30c7\u30fc\u30bf\u306f\u4ee5\u524d\u306b\u5236\u9650\u3055\u308c\u305f\u3002\u672c\u7814\u7a76\u306f\u3001\u524d\u7acb\u817a\u30ac\u30f3\u3092\u624b\u8853\u307e\u305f\u306f\u653e\u5c04\u7dda\u7642\u6cd5\u3067\u6cbb\u7642\u3057\u3066\u304a\u3044\u305fProstate Strategic Urologic Research Endeavor\uff08CaPSURE\uff09\u30c7\u30fc\u30bf\u30d9\u30fc\u30b9\u306eCancer\u3067\u3001\u307b\u307c6,000\u4eba\u306e\u7537\u6027\u3092\u898b\u305f\u3002
\n\u95a2\u4fc2\u3059\u308b\u7537\u6027 \u2015 37\u30d1\u30fc\u30bb\u30f3\u30c8 \u2015 \u306e\u3046\u3061\u306e\u7d042,200\u4eba\u306f\u3001\u6297\u51dd\u56fa\u5264\uff08\u30ef\u30eb\u30d5\u30a1\u30ea\u30f3\u3001\u30af\u30ed\u30d4\u30c9\u30b0\u30ec\u30eb\u3001\u30a8\u30ce\u30ad\u30b5\u30d1\u30ea\u30f3\u304a\u3088\u3073\uff0f\u307e\u305f\u306f\u30a2\u30b9\u30d4\u30ea\u30f3\uff09\u3092\u6295\u4e0e\u3055\u308c\u3066\u3044\u305f\u3002\u524d\u7acb\u817a\u30ac\u30f3\u304b\u3089\u306e\u6b7b\u4ea1\u30ea\u30b9\u30af\u306f\u3001\u6297\u51dd\u56fa\u5264\u3092\u670d\u7528\u3057\u3066\u3044\u308b\u305d\u308c\u3089\u3068\u305d\u3046\u3067\u306f\u306a\u304b\u3063\u305f\u4eba\u3005\u306e\u9593\u306b\u6bd4\u8f03\u3055\u308c\u305f\u3002
\n\u975e\u6297\u51dd\u56fa\u6027\u7fa4 \u2015 3\u30d1\u30fc\u30bb\u30f3\u30c8\u5bfe8\u30d1\u30fc\u30bb\u30f3\u30c8\u3001\u305d\u308c\u305e\u308c \u2015 \u3068\u6bd4\u8f03\u3057\u3066\u3001\u6240\u898b\u306f\u524d\u7acb\u817a\u30ac\u30f3\u304b\u3089\u306e10\u5e74\u306e\u6b7b\u4ea1\u7387\u304c\u6297\u51dd\u56fa\u5264\u3092\u670d\u7528\u3057\u3066\u3044\u308b\u7fa4\u3067\u6709\u610f\u306b\u3088\u308a\u4f4e\u3044\u3053\u3068\u3092\u8a3c\u660e\u3057\u305f\u3002\u764c\u518d\u767a\u3068\u9aa8\u8ee2\u79fb\u306e\u3082\u30ea\u30b9\u30af\u306f\u3001\u6709\u610f\u306b\u3088\u308a\u4f4e\u304b\u3063\u305f\u3002\u4ed6\u306e\u30bf\u30a4\u30d7\u306e\u6297\u51dd\u56fa\u5264\u3068\u306f\u5bfe\u7167\u7684\u306b\u3001\u66f4\u306a\u308b\u5206\u6790\u306f\u3001\u3053\u306e\u6709\u76ca\u6027\u304c\u4e3b\u306b\u30a2\u30b9\u30d4\u30ea\u30f3\u3092\u670d\u7528\u3059\u308b\u3053\u3068\u306b\u7531\u6765\u3059\u308b\u3053\u3068\u3092\u793a\u5506\u3057\u305f\u3002
\n\u30a2\u30b9\u30d4\u30ea\u30f3\uff08\u3057\u3070\u3057\u3070\u51e6\u65b9\u3055\u308c\u305f\u304a\u3088\u3073\u6bd4\u8f03\u7684\u5fcd\u5bb9\u6027\u304c\u9ad8\u3044\u85ac\u7269\uff09\u304c\u524d\u7acb\u817a\u30ac\u30f3\u3067\u7d50\u679c\u3092\u6539\u5584\u3059\u308b\u53ef\u80fd\u6027\u304c\u3042\u308b\u3068\u3044\u3046\u793a\u5506\u306f\u7279\u306b\u8208\u5473\u304c\u3042\u308b\u3068\u3001\u524d\u7acb\u817a\u30ac\u30f3\u304c\u7537\u6027\u3068\u30a2\u30e1\u30ea\u30ab\u306e\u7b2c2\u306e\u4e3b\u8981\u306a\u764c\u6bba\u4eba\u8005\u306e\u9593\u3067\u6700\u3082\u666e\u901a\u578b\u975e\u76ae\u819a\u764c\u3067\u3042\u308b\u6642\u304b\u3089\u3001\u30c1\u30e7\u30a6\u535a\u58eb\u304c\u8a00\u3063\u305f\u3002
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\n\u672c\u7814\u7a76\u3068\u95a2\u4fc2\u3057\u3066\u3044\u308b\u4ed6\u306e\u79d1\u5b66\u8005\u306f\u3001\u30b8\u30e3\u30cd\u30c3\u30c8\u30fb\u30ab\u30a6\u30a2\u30f3\uff08\u535a\u58eb\uff09\u3092\u542b\u3081\u308b\u3002\uff16\u6708\u306e\u30c1\u30e3\u30f3\u3068\u30ab\u30ea\u30d5\u30a9\u30eb\u30cb\u30a2\u5927\u5b66\uff08\u30b5\u30f3\u30d5\u30e9\u30f3\u30b7\u30b9\u30b3\uff09\u306e\u30d4\u30fc\u30bf\u30fc\u30fb\u30ad\u30e3\u30ed\u30eb;\u30cf\u30fc\u30d0\u30fc\u30c9\u5927\u5b66\u306e\u30a2\u30f3\u30bd\u30cb\u30fc\u30fb\u30c0\u30df\u30fc\u30b3\u535a\u58eb;\u305d\u3057\u3066\u3001\u30b7\u30ab\u30b4\u5927\u5b66\u306e\u4e0a\u7d1a\u8457\u8005\u30b9\u30bf\u30f3\u30ea\u30fcLiauw\u535a\u58eb\u3002
\n________________________________________
\n\u5b66\u8853\u8a8c\u53c2\u7167\uff1a
\n1.\tK. S.\u30c1\u30e7\u30a6\u3001J. E.\u30ab\u30a6\u30a2\u30f3\u3001J. M.\u30c1\u30e3\u30f3\u3001P. R.\u30ad\u30e3\u30ed\u30eb\u3001A. V.\u30c0\u30df\u30fc\u30b3\u3001S. L. Liauw\u3002\u30a2\u30b9\u30d4\u30ea\u30f3\u4f7f\u7528\u3068\u524d\u7acb\u817a\u5207\u9664\u307e\u305f\u306f\u653e\u5c04\u7dda\u7642\u6cd5\u3067\u6cbb\u7642\u3055\u308c\u308b\u7537\u6027\u306b\u304a\u3051\u308b\u524d\u7acb\u817a\u30ac\u30f3\u6b7b\u4ea1\u7387\u306e\u30ea\u30b9\u30af\u3002Clinical Oncology\uff082012\uff09\u30b8\u30e3\u30fc\u30ca\u30eb;DOI\uff1a10.1200\/JCO.2011.41.0308<\/p>\n
Aspirin and Prostate Cancer<\/p>\n
Aspirin May Help Men With Prostate Cancer Live Longer, Study Suggests
\nScienceDaily (Aug. 28, 2012) \u2014 Men who have been treated for prostate cancer, either with surgery or radiation, could benefit from taking aspirin regularly, says a new study that includes a researcher at UT Southwestern Medical Center.
\nTaking aspirin is associated with a lower risk of death from prostate cancer, especially in men with high risk disease, according to a multicenter study published in the August 28 issue of the Journal of Clinical Oncology. Dr. Kevin Choe, assistant professor of radiation oncology at UT Southwestern, is first author of the paper.
\nPreclinical studies have shown that aspirin and other anticoagulation medications may inhibit cancer growth and metastasis, but clinical data have been limited previously. The study looked at almost 6,000 men in the Cancer of the Prostate Strategic Urologic Research Endeavor (CaPSURE) database who had prostate cancer treated with surgery or radiotherapy.
\nAbout 2,200 of the men involved \u2014 37 percent \u2014 were receiving anticoagulants (warfarin, clopidogrel, enoxaparin, and\/or aspirin). The risk of death from prostate cancer was compared between those taking anticoagulants and those who were not.
\nThe findings demonstrated that 10-year mortality from prostate cancer was significantly lower in the group taking anticoagulants, compared to the non-anticoagulant group \u2014 3 percent versus 8 percent, respectively. The risks of cancer recurrence and bone metastasis also were significantly lower. Further analysis suggested that this benefit was primarily derived from taking aspirin, as opposed to other types of anticoagulants.
\nThe suggestion that aspirin, a frequently prescribed and relatively well-tolerated medication, may improve outcomes in prostate cancer is of particular interest, Dr. Choe said, since prostate cancer is the most common non-skin cancer among men and the second-leading cancer killer in the U.S.
\n\u201cThe results from this study suggest that aspirin prevents the growth of tumor cells in prostate cancer, especially in high-risk prostate cancer, for which we do not have a very good treatment currently,\u201d Dr. Choe said. \u201cBut we need to better understand the optimal use of aspirin before routinely recommending it to all prostate cancer patients.\u201d
\nOther scientists involved with the study include Janet Cowan, Drs. June Chan, and Peter Carroll of the University of California, San Francisco; Dr. Anthony D\u2019Amico of Harvard University; and senior author Dr. Stanley Liauw of the University of Chicago.
\n________________________________________
\nJournal Reference:
\n2.\tK. S. Choe, J. E. Cowan, J. M. Chan, P. R. Carroll, A. V. D\u2019Amico, S. L. Liauw. Aspirin Use and the Risk of Prostate Cancer Mortality in Men Treated With Prostatectomy or Radiotherapy. Journal of Clinical Oncology, 2012; DOI: 10.1200\/JCO.2011.41.0308<\/p>\n","protected":false},"excerpt":{"rendered":"
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