{"id":2740,"date":"2017-11-08T17:24:33","date_gmt":"2017-11-08T08:24:33","guid":{"rendered":"https:\/\/www.taiyou-clinic.jp\/blog\/?p=2740"},"modified":"2017-11-08T17:24:33","modified_gmt":"2017-11-08T08:24:33","slug":"ips%e7%b4%b0%e8%83%9e%e3%81%a7%e3%82%b5%e3%83%ab%e3%81%ae%e3%83%91%e3%83%bc%e3%82%ad%e3%83%b3%e3%82%bd%e3%83%b3%e7%97%85%e7%97%87%e7%8a%b6%e3%81%8c%e7%b7%a9%e5%92%8c","status":"publish","type":"post","link":"https:\/\/www.taiyou-clinic.jp\/blog\/archives\/2740","title":{"rendered":"iPS\u7d30\u80de\u3067\u30b5\u30eb\u306e\u30d1\u30fc\u30ad\u30f3\u30bd\u30f3\u75c5\u75c7\u72b6\u304c\u7de9\u548c"},"content":{"rendered":"<p><span>iPS<\/span>\u7d30\u80de\u3067\u30b5\u30eb\u306e\u30d1\u30fc\u30ad\u30f3\u30bd\u30f3\u75c5\u75c7\u72b6\u304c\u7de9\u548c<span>\u00a0 <\/span><\/p>\n<p><span>\u00a0<\/span><\/p>\n<p>\u30d1\u30fc\u30ad\u30f3\u30bd\u30f3\u75c5\u306e\u60a3\u8005\u306b\u3068\u3063\u3066\u306f\u6717\u5831\u3060\u3002\u305f\u3060\u3057\u3001\uff25\uff33\u306a\u3089\u4f5c\u6210\u8cbb\u7528\u304c\u5b89\u304f\u6e08\u3080\u304c\u514d\u75ab\u6291\u5236\u5264\u3092\u4f7f\u7528\u3057\u306a\u3051\u308c\u3070\u306a\u3089\u306a\u3044\u3068\u3044\u3046\u554f\u984c\u304c\u3042\u308a\u3001\uff29\uff30\uff33\u306a\u3089\u4e00\u4eba\uff15\uff10\uff10\uff10\u4e07\u5186\u3068\u8a00\u308f\u308c\u3066\u3044\u308b\u8cbb\u7528\u304c\u639b\u304b\u308b\u3068\u3044\u3046\u554f\u984c\u304c\u3042\u308b\u3002\u30d2\u30c8\uff28\uff2c\uff21\u578b\u306e\u4e2d\u3067\u3082\u6bd4\u8f03\u7684\u5206\u5e03\u306e\u591a\u3044\uff28\uff2c\uff21\u306b\u9650\u3063\u3066\uff29\uff30\uff33\u7d30\u80de\u3092\u5927\u91cf\u306b\u4f5c\u308b\u306e\u304c\u305d\u306e\u7d4c\u6e08\u7684\u306a\u5408\u7406\u6027\u306e\u69d8\u3067\u3042\u308b\u3002\u7d50\u5c40\u306f\u514d\u75ab\u6291\u5236\u5264\u3092\u4f7f\u7528\u3057\u306a\u3051\u308c\u3070\u306a\u3089\u306a\u3044\u304c\u3001\u3059\u3079\u3066\u304c\u767a\u764c\u306b\u306a\u308b\u308f\u3051\u3067\u306f\u306a\u3044\u304b\u3089\u305d\u306e\u90e8\u5206\u306e\u30c7\u30e1\u30ea\u30c3\u30c8\u306f\u76ee\u3092\u3064\u3080\u308d\u3046\u3068\u3044\u3046\u308f\u3051\u3067\u3042\u308b\u3002\u78ba\u304b\u306b\u305d\u308c\u304c\u5408\u7406\u7684\u3060\u3068\u601d\u3046\u3002<\/p>\n<p><span>http:\/\/www.natureasia.com\/ja-jp\/ndigest\/v14\/n11\/iPS%E7%B4%B0%E8%83%9E%E3%81%A7%E3%82%B5%E3%83%AB%E3%81%AE%E3%83%91%E3%83%BC%E3%82%AD%E3%83%B3%E3%82%BD%E3%83%B3%E7%97%85%E7%97%87%E7%8A%B6%E3%81%8C%E7%B7%A9%E5%92%8C\/89718<\/span><\/p>\n<p><span>Nature <\/span>\u30c0\u30a4\u30b8\u30a7\u30b9\u30c8<span> Vol. 14 No. 11 | doi : 10.1038\/ndigest.2017.171102 <\/span><\/p>\n<p><span>\u00a0<\/span><\/p>\n<p>\u539f\u6587\uff1a<span>Nature (2017-08-30) | doi: 10.1038\/nature.2017.22531 | Reprogrammed cells relieve Parkinson's symptoms in trials \uf0f6 Ewen Callaway<\/span><\/p>\n<p><span>\u00a0<\/span><\/p>\n<p><span>iPS<\/span>\u7d30\u80de\u304b\u3089\u4f5c\u88fd\u3057\u305f\u30cb\u30e5\u30fc\u30ed\u30f3\u3092\u30d1\u30fc\u30ad\u30f3\u30bd\u30f3\u75c5\u30e2\u30c7\u30eb\u306e\u30b5\u30eb\u306b\u79fb\u690d\u3057\u305f\u3068\u3053\u308d\u3001<span>2<\/span>\u5e74\u9593\u306b\u308f\u305f\u3063\u3066\u75c7\u72b6\u306e\u6539\u5584\u304c\u89b3\u5bdf\u3055\u308c\u3001\u305d\u306e\u9593\u3001\u79fb\u690d\u30cb\u30e5\u30fc\u30ed\u30f3\u306f\u6709\u5bb3\u306a\u4f5c\u7528\u3092\u5f15\u304d\u8d77\u3053\u3055\u306a\u304b\u3063\u305f\u3002<\/p>\n<p><span>\u00a0<\/span><\/p>\n<p>\u4eac\u90fd\u5927\u5b66\u306e\u5e79\u7d30\u80de\u79d1\u5b66\u8005\u3001\u9ad9\u6a4b\u6df3\u3089\u306f\u3001\u4eba\u5de5\u591a\u80fd\u6027\u5e79\uff08<span>iPS<\/span>\uff09\u7d30\u80de\u304b\u3089\u4f5c\u88fd\u3057\u305f\u30cb\u30e5\u30fc\u30ed\u30f3\u3092\u30d1\u30fc\u30ad\u30f3\u30bd\u30f3\u75c5\u30e2\u30c7\u30eb\u306e\u30b5\u30eb\u306e\u8133\u306b\u79fb\u690d\u3059\u308b\u3068\u3044\u3046\u5b9f\u9a13\u7684\u6cbb\u7642\u3067\u6709\u671b\u306a\u7d50\u679c\u3092\u5f97\u305f\u3053\u3068\u3092\u3001<span>2017<\/span>\u5e74<span>8<\/span>\u6708<span>31<\/span>\u65e5\u53f7\u306e<span>Nature<\/span>\u306b\u5831\u544a\u3057\u305f<span>1<\/span>\u3002\u5f7c\u3089\u306f\u3001\u3053\u306e\u6cbb\u7642\u306b\u3088\u3063\u3066\u30d1\u30fc\u30ad\u30f3\u30bd\u30f3\u75c5\u306e\u75c7\u72b6\u304c\u6539\u5584\u3059\u308b\u3053\u3068\u3001\u307e\u305f\u3001\u3053\u306e\u6cbb\u7642\u304c\u5b89\u5168\u3067\u3042\u308b\u3089\u3057\u3044\u3053\u3068\u3092\u793a\u3057\u3066\u3044\u308b\u3002<\/p>\n<p><span>\u00a0<\/span><\/p>\n<p>\u79fb\u690d\u3055\u308c\u305f\u7d30\u80de\u304c\u5c11\u306a\u304f\u3068\u3082<span>2<\/span>\u5e74\u9593\u3001\u4f53\u306b\u6709\u5bb3\u306a\u5f71\u97ff\u3092\u53ca\u307c\u3059\u3053\u3068\u306a\u304f\u8133\u3067\u751f\u5b58\u3057\u7d9a\u3051\u305f\u3001\u3068\u3044\u3046\u4eca\u56de\u306e\u77e5\u898b\u306f\u91cd\u8981\u306a\u3082\u306e\u3067\u3042\u308a\u3001\u5e79\u7d30\u80de\u3092\u4f7f\u3063\u305f\u30d1\u30fc\u30ad\u30f3\u30bd\u30f3\u75c5\u6cbb\u7642\u306e\u81e8\u5e8a\u8a66\u9a13\uff08\u6cbb\u9a13\uff09\u306e\u5b9f\u65bd\u3092\u8a08\u753b\u3059\u308b\u7814\u7a76\u8005\u305f\u3061\u3092\u5927\u304d\u304f\u5f8c\u62bc\u3057\u3059\u308b\u3068\u8003\u3048\u3089\u308c\u308b\u3002<\/p>\n<p><span>\u00a0<\/span><\/p>\n<p>\u9ad9\u6a4b\u6df3\u3089\u306e\u7814\u7a76\u30c1\u30fc\u30e0\u306f\u3001<span>2018<\/span>\u5e74\u672b\u307e\u3067\u306b\u3001<span>iPS<\/span>\u7d30\u80de\u304b\u3089\u4f5c\u88fd\u3057\u305f\u30cb\u30e5\u30fc\u30ed\u30f3\u3092\u79fb\u690d\u3059\u308b\u6cbb\u9a13\u3092\u59cb\u3081\u308b\u8a08\u753b\u3060\u3068\u3044\u3046\u3002<\/p>\n<p><span>\u00a0<\/span><\/p>\n<p>\u73fe\u5728\u3001\u4e16\u754c\u4e2d\u3067\u8907\u6570\u306e\u7814\u7a76\u30c1\u30fc\u30e0\u304c\u3001\u5e79\u7d30\u80de\u3092\u4f7f\u3063\u305f\u30d1\u30fc\u30ad\u30f3\u30bd\u30f3\u75c5\u6cbb\u7642\u6cd5\u306b\u3064\u3044\u3066\u7570\u306a\u308b\u30a2\u30d7\u30ed\u30fc\u30c1\u3067\u7814\u7a76\u3057\u3066\u304a\u308a\u3001\u3044\u304f\u3064\u3082\u306e\u6cbb\u9a13\u304c\u8fd1\u304f\u5b9f\u65bd\u3055\u308c\u308b\u4e88\u5b9a\u3060\u3002\u9ad9\u6a4b\u3089\u306e\u3053\u306e\u7814\u7a76\u6210\u679c\u306f\u3001\u305d\u3046\u3057\u305f\u4ed6\u306e\u7814\u7a76\u30c1\u30fc\u30e0\u306b\u3082\u6d3b\u6c17\u3092\u4e0e\u3048\u308b\u3060\u308d\u3046\u3002<\/p>\n<p><span>\u00a0<\/span><\/p>\n<p><span>Nature<\/span>\u306f\u3053\u306e\u6700\u65b0\u306e\u7814\u7a76\u3092\u5206\u6790\u3057\u3001\u3053\u308c\u304c\u5e79\u7d30\u80de\u6cbb\u7642\u306e\u672a\u6765\u306b\u3069\u306e\u3088\u3046\u306a\u610f\u5473\u3092\u6301\u3064\u304b\u3092\u691c\u8a0e\u3057\u305f\u3002<\/p>\n<p><span>\u00a0<\/span><\/p>\n<p>\u5e79\u7d30\u80de\u306f\u306a\u305c\u30d1\u30fc\u30ad\u30f3\u30bd\u30f3\u75c5\u306e\u6709\u671b\u306a\u6cbb\u7642\u6cd5\u306a\u306e\u304b\uff1f<\/p>\n<p><span>\u00a0<\/span><\/p>\n<p>\u30d1\u30fc\u30ad\u30f3\u30bd\u30f3\u75c5\u306f\u3001\u4e2d\u8133\u306e\u9ed2\u8cea\u3068\u547c\u3070\u308c\u308b\u9818\u57df\u306b\u304a\u3044\u3066\u30c9\u30fc\u30d1\u30df\u30f3\u7523\u751f\u30cb\u30e5\u30fc\u30ed\u30f3\uff08\u30c9\u30fc\u30d1\u30df\u30f3\u3068\u547c\u3070\u308c\u308b\u795e\u7d4c\u4f1d\u9054\u7269\u8cea\u3092\u4f5c\u308b\uff09\u304c\u6b7b\u306c\u3053\u3068\u3067\u5f15\u304d\u8d77\u3053\u3055\u308c\u308b\u795e\u7d4c\u5909\u6027\u75be\u60a3\u3067\u3042\u308b\u3002\u3053\u306e\u30cb\u30e5\u30fc\u30ed\u30f3\u306f\u904b\u52d5\u306b\u95a2\u308f\u3063\u3066\u3044\u308b\u306e\u3067\u3001\u60a3\u8005\u306b\u306f\u3053\u306e\u75c5\u6c17\u306b\u7279\u5fb4\u7684\u306a\u632f\u6226\u3068\u7b4b\u5f37\u525b\u304c\u898b\u3089\u308c\u308b\u3088\u3046\u306b\u306a\u308b\u3002\u73fe\u5728\u306e\u6cbb\u7642\u6cd5\u306f\u3053\u3046\u3057\u305f\u75c7\u72b6\u306b\u5bfe\u51e6\u3059\u308b\u3082\u306e\u3067\u3042\u308a\u3001\u75c5\u6c17\u306e\u6839\u672c\u306e\u539f\u56e0\u306b\u5bfe\u3059\u308b\u6cbb\u7642\u6cd5\u306f\u4eca\u306e\u3068\u3053\u308d\u306a\u3044\u3002<\/p>\n<p><span>\u00a0<\/span><\/p>\n<p>\u7814\u7a76\u8005\u305f\u3061\u306f\u3001\u30d1\u30fc\u30ad\u30f3\u30bd\u30f3\u75c5\u60a3\u8005\u306e\u6b7b\u3093\u3067\u3057\u307e\u3063\u305f\u30c9\u30fc\u30d1\u30df\u30f3\u7523\u751f\u30cb\u30e5\u30fc\u30ed\u30f3\u3092\u3001\u591a\u80fd\u6027\u5e79\u7d30\u80de\uff08\u4f53\u5185\u306e\u3042\u3089\u3086\u308b\u30bf\u30a4\u30d7\u306e\u7d30\u80de\u3092\u4f5c\u308a\u51fa\u305b\u308b\uff09\u3092\u7528\u3044\u3066\u7f6e\u63db\u3059\u308c\u3070\u3001\u75c5\u6c17\u306e\u9032\u884c\u3092\u98df\u3044\u6b62\u3081\u305f\u308a\u75c5\u6c17\u3092\u56de\u5fa9\u3055\u305b\u305f\u308a\u3059\u308b\u3053\u3068\u304c\u3067\u304d\u308b\u306e\u3067\u306f\u306a\u3044\u304b\u3068\u8003\u3048\u3001\u8ffd\u7a76\u3057\u3066\u304d\u305f\u3002\u30d2\u30c8\u80da\u304b\u3089\u5f97\u3089\u308c\u305f\u80da\u6027\u5e79\uff08<span>ES<\/span>\uff09\u7d30\u80de\u306b\u306f\u3053\u3046\u3057\u305f\u80fd\u529b\u304c\u3042\u308b\u304c\u3001\u4eba\u306e\u751f\u547d\u306e\u840c\u82bd\u3067\u3042\u308b\u80da\u3092\u7834\u58ca\u3059\u308b\u5fc5\u8981\u304c\u3042\u308b\u305f\u3081\u3001\u502b\u7406\u7684\u306a\u8b70\u8ad6\u306e\u5bfe\u8c61\u3068\u306a\u3063\u3066\u3044\u308b\u3002<span>iPS<\/span>\u7d30\u80de\u306f\u540c\u69d8\u306e\u591a\u80fd\u6027\u3092\u6301\u3064\u304c\u3001\u6210\u4f53\u306e\u7d30\u80de\u3092\u8a98\u5c0e\u3057\u3066<span>ES<\/span>\u7d30\u80de\u69d8\u306e\u72b6\u614b\u306b\u3057\u305f\u3082\u306e\u3067\u3042\u308b\u305f\u3081\u3001\u502b\u7406\u7684\u306a\u61f8\u5ff5\u306f\u306a\u3044\u3002<\/p>\n<p><span>\u00a0<\/span><\/p>\n<p>\u4eca\u56de\u306e\u6700\u65b0\u306e\u7814\u7a76\u3067\u767a\u898b\u3055\u308c\u305f\u3053\u3068\u306f\uff1f<\/p>\n<p><span>\u00a0<\/span><\/p>\n<p>\u9ad9\u6a4b\u3089\u306e\u30c1\u30fc\u30e0\u306f\u307e\u305a\u3001\u5065\u5e38\u8005\u3068\u30d1\u30fc\u30ad\u30f3\u30bd\u30f3\u75c5\u60a3\u8005\u306e\u4e21\u65b9\u304b\u3089\u4f5c\u51fa\u3057\u305f<span>iPS<\/span>\u7d30\u80de\u304b\u3089\u30c9\u30fc\u30d1\u30df\u30f3\u7523\u751f\u30cb\u30e5\u30fc\u30ed\u30f3\u3092\u4f5c\u88fd\u3057\u305f\u3002\u305d\u3057\u3066\u3001\u30ab\u30cb\u30af\u30a4\u30b6\u30eb\u306e\u30c9\u30fc\u30d1\u30df\u30f3\u7523\u751f\u30cb\u30e5\u30fc\u30ed\u30f3\u3092\u6bd2\u7d20\u306b\u3088\u3063\u3066\u6bba\u3057\u3066\u30d1\u30fc\u30ad\u30f3\u30bd\u30f3\u75c5\u72b6\u614b\u3092\u8a98\u5c0e\u3057\u305f\u5f8c\u306b\u3001<span>iPS<\/span>\u7d30\u80de\u304b\u3089\u4f5c\u88fd\u3057\u305f\u30cb\u30e5\u30fc\u30ed\u30f3\u3092\u79fb\u690d\u3057\u305f\u3002<\/p>\n<p><span>\u00a0<\/span><\/p>\n<p>\u305d\u306e\u7d50\u679c\u3001\u79fb\u690d\u3055\u308c\u305f\u30cb\u30e5\u30fc\u30ed\u30f3\u306f\u5c11\u306a\u304f\u3068\u3082<span>2<\/span>\u5e74\u9593\u751f\u5b58\u3057\u3001\u30b5\u30eb\u306e\u30cb\u30e5\u30fc\u30ed\u30f3\u3068\u306e\u795e\u7d4c\u56de\u8def\u304c\u5f62\u6210\u3055\u308c\u305f\u3002\u7d30\u80de\u6cbb\u7642\u3092\u53d7\u3051\u305f\u30b5\u30eb\u304c\u30b1\u30fc\u30b8\u306e\u4e2d\u3067\u983b\u7e41\u306b\u52d5\u304f\u3088\u3046\u306b\u306a\u308b\u306e\u304c\u89b3\u5bdf\u3055\u308c\u305f\u306e\u306f\u3001\u3053\u3046\u3057\u305f\u795e\u7d4c\u56de\u8def\u304c\u5f62\u6210\u3055\u308c\u305f\u3053\u3068\u306b\u3088\u308b\u53ef\u80fd\u6027\u304c\u3042\u308b\u3002<\/p>\n<p><span>\u00a0<\/span><\/p>\n<p>\u3053\u306e\u7814\u7a76\u306f\u306a\u305c\u91cd\u8981\u306a\u306e\u304b\uff1f<\/p>\n<p><span>\u00a0<\/span><\/p>\n<p>\u91cd\u8981\u306a\u306e\u306f\u3001\u9ad9\u6a4b\u3089\u306e\u30c1\u30fc\u30e0\u306e\u7814\u7a76\u3067\u306f\u3001\u79fb\u690d\u3057\u305f\u7d30\u80de\u304c\u816b\u760d\u5316\u3057\u305f\u3053\u3068\u3092\u793a\u3059\u8a3c\u62e0\u3084\u3001\u514d\u75ab\u6291\u5236\u5264\u306b\u3088\u3063\u3066\u5236\u5fa1\u4e0d\u80fd\u306a\u514d\u75ab\u53cd\u5fdc\u304c\u5f15\u304d\u8d77\u3053\u3055\u308c\u305f\u8a3c\u62e0\u304c\u5168\u304f\u898b\u3089\u308c\u306a\u304b\u3063\u305f\u3053\u3068\u3060\u3002\u524d\u8005\u306f\u3001\u591a\u80fd\u6027\u7d30\u80de\u306b\u3088\u308b\u6cbb\u7642\u306b\u304a\u3044\u3066\u3001\u4e3b\u306a\u61f8\u5ff5\u4e8b\u9805\u3068\u3055\u308c\u308b\u3002<\/p>\n<p><span>\u00a0<\/span><\/p>\n<p>\u300c\u30d2\u30c8\u306b\u7d30\u80de\u3092\u79fb\u690d\u3059\u308b\u7814\u7a76\u306b\u81ea\u4fe1\u3092\u6301\u3063\u3066\u9032\u3080\u305f\u3081\u306b\u306f\u3001\u4e8b\u524d\u306b\u8abf\u3079\u3066\u304a\u304b\u306d\u3070\u306a\u3089\u306a\u3044\u4e00\u9023\u306e\u91cd\u8981\u306a\u554f\u984c\u304c\u3042\u308a\u307e\u3059\u3002\u9ad9\u6a4b\u3089\u306e\u7814\u7a76\u306f\u305d\u3046\u3057\u305f\u554f\u984c\u306b\u53d6\u308a\u7d44\u3093\u3067\u3044\u308b\u306e\u3067\u3059\u300d\u3068\u3001\u30eb\u30f3\u30c9\u5927\u5b66\uff08\u30b9\u30a6\u30a7\u30fc\u30c7\u30f3\uff09\u306e\u795e\u7d4c\u79d1\u5b66\u8005<span>Anders Bjorklund<\/span>\u306f\u8a00\u3046\u3002<\/p>\n<p><span>\u00a0<\/span><\/p>\n<p>\u6cbb\u9a13\u306f\u3044\u3064\u59cb\u307e\u308a\u3001\u3069\u306e\u3088\u3046\u306b\u884c\u3046\u4e88\u5b9a\u306a\u306e\u304b\uff1f<\/p>\n<p><span>\u00a0<\/span><\/p>\n<p>\u300c\u6211\u3005\u306f\u3001<span>2018<\/span>\u5e74\u672b\u307e\u3067\u306b\u306f\u6cbb\u9a13\u3092\u59cb\u3081\u305f\u3044\u3068\u8003\u3048\u3066\u3044\u307e\u3059\u300d\u3068\u9ad9\u6a4b\u3002\u3053\u308c\u306f\u3001<span>iPS<\/span>\u7d30\u80de\u306b\u3088\u308b\u30d1\u30fc\u30ad\u30f3\u30bd\u30f3\u75c5\u6cbb\u7642\u306e\u521d\u3081\u3066\u306e\u6cbb\u9a13\u3068\u306a\u308b\u3060\u308d\u3046\u3002\u306a\u304a\u3001\u30d2\u30c8\u3078\u306e<span>iPS<\/span>\u7d30\u80de\u79fb\u690d\u304c\u521d\u3081\u3066\u884c\u308f\u308c\u305f\u306e\u306f<span>2014<\/span>\u5e74\u3067\u3001\u6700\u521d\u306e\u60a3\u8005\u306f\u52a0\u9f62\u9ec4\u6591\u5909\u6027\u306e<span>70<\/span>\u4ee3\u306e\u65e5\u672c\u4eba\u5973\u6027\u3067\u3042\u3063\u305f\u3002<\/p>\n<p><span>\u00a0<\/span><\/p>\n<p><span>iPS<\/span>\u7d30\u80de\u306f\u3001\u7406\u8ad6\u4e0a\u3001\u81ea\u5206\u81ea\u8eab\u306e<span>iPS<\/span>\u7d30\u80de\u3092\u7528\u3044\u305f\u79fb\u690d\u6cbb\u7642\u304c\u53ef\u80fd\u3068\u306a\u308b\u3002\u3053\u306e\u305f\u3081\u3001\u5916\u6765\u7d44\u7e54\u306e\u79fb\u690d\u3067\u61f8\u5ff5\u3055\u308c\u308b\u62d2\u7d76\u53cd\u5fdc\u3092\u6291\u3048\u308b\u305f\u3081\u306e\u85ac\u306f\u5fc5\u8981\u306a\u3044\u3002<\/p>\n<p><span>\u00a0<\/span><\/p>\n<p>\u3057\u304b\u3057\u3001\u60a3\u8005\u3054\u3068\u306b\u81ea\u5df1<span>iPS<\/span>\u7d30\u80de\u3092\u4f5c\u308b\u306b\u306f\u8cbb\u7528\u304c\u304b\u304b\u308a\u3001\u307e\u305f\u3001\u8a98\u5c0e\u3057\u3066\u57f9\u990a\u3059\u308b\u306b\u306f<span>2<\/span>\u30ab\u6708\u307b\u3069\u304b\u304b\u308b\u53ef\u80fd\u6027\u304c\u3042\u308b\u3068\u9ad9\u6a4b\u306f\u8ff0\u3079\u308b\u3002\u305d\u3053\u3067\u9ad9\u6a4b\u3089\u306f\u307e\u305a\u3001\u983b\u5ea6\u306e\u9ad8\u3044<span>HLA<\/span>\uff08<span>Human Leukocyte Antigen<\/span>\uff1b\u30d2\u30c8\u767d\u8840\u7403\u578b\u6297\u539f\uff09\u578b\u306e\u5065\u5e38\u8005\u306e\u7d30\u80de\u304b\u3089<span>iPS<\/span>\u7d30\u80de\u682a\u3092\u6a39\u7acb\u3057\u3001\u6cbb\u7642\u3092\u884c\u3046\u30d1\u30fc\u30ad\u30f3\u30bd\u30f3\u75c5\u60a3\u8005\u306b<span>HLA<\/span>\u578b\u304c\u9069\u5408\u3059\u308b<span>iPS<\/span>\u7d30\u80de\u682a\u3092\u79fb\u690d\u3059\u308b\u8a08\u753b\u3092\u7acb\u3066\u3066\u3044\u308b\u3002\u3053\u308c\u306a\u3089\u3070\u3001\u8cbb\u7528\u3092\u6291\u3048\u3064\u3064\u3001\u62d2\u7d76\u53cd\u5fdc\uff08\u3068\u3001\u62d2\u7d76\u53cd\u5fdc\u3092\u548c\u3089\u3052\u308b\u85ac\uff09\u3092\u6700\u5c0f\u9650\u306b\u6291\u3048\u308b\u3053\u3068\u304c\u671f\u5f85\u3067\u304d\u308b\u3002<\/p>\n<p><span>\u00a0<\/span><\/p>\n<p>\u9ad9\u6a4b\u3089\u306e\u7814\u7a76\u30c1\u30fc\u30e0\u306f\u3001<span>2017<\/span>\u5e74<span>8<\/span>\u6708\u306b<span>Nature Communications<\/span>\u306b\u63b2\u8f09\u3055\u308c\u305f\u95a2\u9023\u8ad6\u6587<span>2<\/span>\u3067\u3001\u30ab\u30cb\u30af\u30a4\u30b6\u30eb\u306e<span>iPS<\/span>\u7d30\u80de\u304b\u3089\u8a98\u5c0e\u3057\u305f\u30cb\u30e5\u30fc\u30ed\u30f3\u3092\u3001\u5225\u306e\u500b\u4f53\u306b\u79fb\u690d\u3057\u3066\u3044\u308b\u3002\u305d\u306e\u7d50\u679c\u3001<span>HLA<\/span>\u578b\u304c\u9069\u5408\u3059\u308b\u30b5\u30eb\u540c\u58eb\u306e\u30cb\u30e5\u30fc\u30ed\u30f3\u306e\u79fb\u690d\u3067\u5f15\u304d\u8d77\u3053\u3055\u308c\u308b\u514d\u75ab\u62d2\u7d76\u306f\u5f31\u3044\u3053\u3068\u304c\u5206\u304b\u3063\u305f\u3002<\/p>\n<p><span>\u00a0<\/span><\/p>\n<p>\u5e79\u7d30\u80de\u3092\u7528\u3044\u305f\u30d1\u30fc\u30ad\u30f3\u30bd\u30f3\u75c5\u6cbb\u7642\u3068\u3057\u3066\u8a66\u9a13\u4e2d\u306e\u3082\u306e\u306b\u306f\u3001\u4ed6\u306b\u3069\u306e\u3088\u3046\u306a\u3082\u306e\u304c\uff1f<\/p>\n<p><span>\u00a0<\/span><\/p>\n<p><span>2017<\/span>\u5e74\u306e\u521d\u3081\u306b\u306f\u3001\u4e2d\u56fd\u4eba\u7814\u7a76\u8005\u305f\u3061\u304c\u5225\u306e\u30a2\u30d7\u30ed\u30fc\u30c1\u306b\u3088\u308b\u8a66\u9a13\u3092\u958b\u59cb\u3057\u305f\u3002\u3053\u306e\u8a66\u9a13\u3067\u306f\u3001<span>ES<\/span>\u7d30\u80de\u304b\u3089\u4f5c\u88fd\u3057\u305f\u795e\u7d4c\u524d\u99c6\u7d30\u80de\u3092\u60a3\u8005\u306b\u79fb\u690d\u3059\u308b\u3002\u8133\u5185\u3067\u6210\u719f\u3057\u305f\u30c9\u30fc\u30d1\u30df\u30f3\u7523\u751f\u30cb\u30e5\u30fc\u30ed\u30f3\u306b\u5206\u5316\u3055\u305b\u308b\u3053\u3068\u304c\u76ee\u7684\u3060\u3002<span>2016<\/span>\u5e74\u306b\u306f\u3001\u30aa\u30fc\u30b9\u30c8\u30e9\u30ea\u30a2\u306e\u60a3\u8005\u304c\u5225\u306e\u8a66\u9a13\u3067\u3001<span>ES<\/span>\u7d30\u80de\u7531\u6765\u306e\u795e\u7d4c\u524d\u99c6\u7d30\u80de\u306e\u79fb\u690d\u3092\u53d7\u3051\u3066\u3044\u308b\u3002\u3057\u304b\u3057\u3001\u672a\u6210\u719f\u306e\u79fb\u690d\u7d30\u80de\u306f\u767a\u304c\u3093\u6027\u5909\u7570\u3092\u8d77\u3053\u3059\u53ef\u80fd\u6027\u304c\u3042\u308b\u3001\u3068\u61f8\u5ff5\u3092\u8868\u660e\u3057\u305f\u7814\u7a76\u8005\u305f\u3061\u3082\u3044\u308b\u3002<\/p>\n<p><span>\u00a0<\/span><\/p>\n<p>\u4e00\u65b9\u3001<span>GForce-PD<\/span>\u3068\u547c\u3070\u308c\u308b\u30d1\u30fc\u30ad\u30f3\u30bd\u30f3\u75c5\u306b\u5bfe\u3059\u308b\u7d30\u80de\u6cbb\u7642\u30b3\u30f3\u30bd\u30fc\u30b7\u30a2\u30e0\u306b\u5c5e\u3059\u308b\u7814\u7a76\u8005\u305f\u3061\uff08\u9ad9\u6a4b\u3082\u305d\u306e\u4e00\u54e1\uff09\u3082\u3001\u307e\u305f\u5225\u306e\u30a2\u30d7\u30ed\u30fc\u30c1\u3092\u63a1\u7528\u3057\u305f\u6cbb\u9a13\u306e\u6e96\u5099\u3092\u9032\u3081\u3066\u3044\u308b\u3002\u7c73\u56fd\u3001\u30b9\u30a6\u30a7\u30fc\u30c7\u30f3\u3001\u304a\u3088\u3073\u82f1\u56fd\u306e\u30c1\u30fc\u30e0\u304c\u8a08\u753b\u3057\u3066\u3044\u308b\u6cbb\u9a13\u306f\u5168\u3066\u3001<span>ES<\/span>\u7d30\u80de\u304b\u3089\u4f5c\u88fd\u3057\u305f\u30c9\u30fc\u30d1\u30df\u30f3\u7523\u751f\u30cb\u30e5\u30fc\u30ed\u30f3\u3092\u30d2\u30c8\u306b\u79fb\u690d\u3059\u308b\u3068\u3044\u3046\u3082\u306e\u3060\u3002\u65e2\u306b\u6a39\u7acb\u3055\u308c\u305f<span>ES<\/span>\u7d30\u80de\u682a\u306b\u306f\u3001\u3088\u304f\u7814\u7a76\u3055\u308c\u3066\u3044\u3066\u5927\u91cf\u306b\u57f9\u990a\u3067\u304d\u308b\u3068\u3044\u3046\u5229\u70b9\u304c\u3042\u308a\u3001\u305d\u306e\u305f\u3081\u5168\u3066\u306e\u6cbb\u9a13\u53c2\u52a0\u8005\u304c\u6a19\u6e96\u5316\u3055\u308c\u305f\u6cbb\u7642\u3092\u53d7\u3051\u308b\u3053\u3068\u304c\u3067\u304d\u308b\u3068\u3001\u540c\u3058\u304f<span>GForce-PD<\/span>\u30b3\u30f3\u30bd\u30fc\u30b7\u30a2\u30e0\u306e\u30e1\u30f3\u30d0\u30fc\u3067\u3042\u308b<span>Bjorklund<\/span>\u306f\u8ff0\u3079\u308b\u3002<\/p>\n<p><span>\u00a0<\/span><\/p>\n<p>\u30b9\u30af\u30ea\u30d7\u30b9\u7814\u7a76\u6240\uff08\u7c73\u56fd\u30ab\u30ea\u30d5\u30a9\u30eb\u30cb\u30a2\u5dde\u30e9\u30db\u30e4\uff09\u306e\u5e79\u7d30\u80de\u79d1\u5b66\u8005<span>Jeanne Loring<\/span>\u306f\u3001\u60a3\u8005\u81ea\u8eab\u306e\u7d30\u80de\u304b\u3089\u4f5c\u88fd\u3057\u305f<span>iPS<\/span>\u7d30\u80de\u7531\u6765\u306e\u30cb\u30e5\u30fc\u30ed\u30f3\u3092\u79fb\u690d\u3059\u308b\u3068\u3044\u3046\u65b9\u6cd5\u3092\u652f\u6301\u3057\u3066\u3044\u308b\u3002\u9ad8\u4fa1\u3067\u306f\u3042\u308b\u304c\u3001\u3053\u306e\u30a2\u30d7\u30ed\u30fc\u30c1\u306a\u3089\u526f\u4f5c\u7528\u304c\u554f\u984c\u3068\u306a\u308b\u514d\u75ab\u6291\u5236\u85ac\u3092\u4f7f\u7528\u3057\u306a\u3044\u3067\u6e08\u3080\u3068\u5f7c\u5973\u306f\u8a00\u3046\u3002\u305d\u3057\u3066\u3001<span>iPS<\/span>\u7d30\u80de\u306f\u60a3\u8005\u4e00\u4eba\u4e00\u4eba\u306e\u305f\u3081\u306b\u65b0\u305f\u306b\u6a39\u7acb\u3059\u308b\u306e\u3067\u3001\u79fb\u690d\u306b\u7528\u3044\u3089\u308c\u308b\u7d30\u80de\u306e\u5206\u88c2\u56de\u6570\u306f\u6bd4\u8f03\u7684\u5c11\u306a\u304f\u3001\u767a\u304c\u3093\u6027\u306e\u5909\u7570\u304c\u751f\u3058\u308b\u30ea\u30b9\u30af\u3092\u6700\u5c0f\u9650\u306b\u3067\u304d\u308b\u3002<span>Loring<\/span>\u306f\u3001\u81ea\u8eab\u306e\u30c1\u30fc\u30e0\u306e\u6cbb\u9a13\u3092<span>2019<\/span>\u5e74\u306b\u306f\u59cb\u3081\u305f\u3044\u3068\u8003\u3048\u3066\u3044\u308b\u3002\u300c\u3053\u308c\u306f\u7af6\u3046\u3079\u304d\u3082\u306e\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002\u79c1\u305f\u3061\u306f\u5168\u3066\u306e\u7814\u7a76\u306e\u6210\u529f\u3092\u5fdc\u63f4\u3057\u3066\u3044\u307e\u3059\u300d\u3068\u5f7c\u5973\u306f\u8a00\u3046\u3002<\/p>\n<p><span>\u00a0<\/span><\/p>\n<p>\u30b9\u30ed\u30fc\u30f3\u30fb\u30b1\u30bf\u30ea\u30f3\u30b0\u8a18\u5ff5\u304c\u3093\u30bb\u30f3\u30bf\u30fc\uff08\u7c73\u56fd\u30cb\u30e5\u30fc\u30e8\u30fc\u30af\u5dde\uff09\u306e\u5e79\u7d30\u80de\u7814\u7a76\u8005<span>Lorenz Studer<\/span>\u306f\u3001<span>ES<\/span>\u7d30\u80de\u304b\u3089\u4f5c\u88fd\u3057\u305f\u30cb\u30e5\u30fc\u30ed\u30f3\u3092\u4f7f\u7528\u3059\u308b\u6cbb\u9a13\u306b\u53d6\u308a\u7d44\u3093\u3067\u3044\u308b\u304c\u3001<span>1<\/span>\u56de\u306e\u79fb\u690d\u306b\u5fc5\u8981\u306a\u7d30\u80de\u6570\u306a\u3069\u3001\u89e3\u6c7a\u3059\u3079\u304d\u554f\u984c\u304c\u307e\u3060\u3042\u308b\u3068\u8ff0\u3079\u308b\u3002\u3057\u304b\u3057\u5f7c\u306f\u3001\u4eca\u56de\u306e\u9ad9\u6a4b\u3089\u306e\u7814\u7a76\u6210\u679c\u306b\u3064\u3044\u3066\u300c\u524d\u3078\u9032\u3080\u6e96\u5099\u304c\u3067\u304d\u305f\u3001\u3068\u3044\u3046\u8a3c\u3067\u3059\u300d\u3068\u8a71\u3059\u3002<\/p>\n<p><span>\u00a0<\/span><\/p>\n<p>\uff08\u7ffb\u8a33\uff1a\u53e4\u5ddd\u5948\u3005\u5b50\uff09<\/p>\n<p><span>\u00a0<\/span><\/p>\n<p><span>\uf15c<\/span>\u53c2\u8003\u6587\u732e<\/p>\n<ol>\n<li><span> Kikuchi, T. et al. Nature 548, 592\u2013596 (2017). <\/span><\/li>\n<li><span> Morizane, A. et al. Nature Communications 8, 385 (2017).<\/span><\/li>\n<\/ol>\n<p><span>\u00a0<\/span><\/p>\n<p><span>\u00a0<\/span><\/p>\n<p><span>\u00a0<\/span><\/p>\n<p><span>\u00a0<\/span><\/p>\n<p><span>\u00a0<\/span><\/p>\n<p><span>\u00a0<\/span><\/p>\n<p><span>\u00a0<\/span><\/p>\n<p><span>\u00a0<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>iPS\u7d30\u80de\u3067\u30b5\u30eb\u306e\u30d1\u30fc\u30ad\u30f3\u30bd\u30f3\u75c5\u75c7\u72b6\u304c\u7de9\u548c\u00a0 \u00a0 \u30d1\u30fc\u30ad\u30f3\u30bd\u30f3\u75c5\u306e\u60a3\u8005\u306b\u3068\u3063\u3066\u306f\u6717\u5831\u3060\u3002\u305f\u3060\u3057\u3001\uff25\uff33\u306a\u3089\u4f5c\u6210\u8cbb\u7528\u304c\u5b89\u304f\u6e08\u3080\u304c\u514d\u75ab\u6291\u5236\u5264\u3092\u4f7f\u7528\u3057\u306a\u3051\u308c\u3070\u306a\u3089\u306a\u3044\u3068\u3044\u3046\u554f\u984c\u304c\u3042\u308a\u3001\uff29\uff30\uff33\u306a\u3089\u4e00\u4eba\uff15\uff10\uff10\uff10\u4e07\u5186\u3068\u8a00\u308f\u308c\u3066\u3044\u308b\u8cbb\u7528 [&hellip;]<\/p>\n","protected":false},"author":6,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[4],"tags":[],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/www.taiyou-clinic.jp\/blog\/wp-json\/wp\/v2\/posts\/2740"}],"collection":[{"href":"https:\/\/www.taiyou-clinic.jp\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.taiyou-clinic.jp\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.taiyou-clinic.jp\/blog\/wp-json\/wp\/v2\/users\/6"}],"replies":[{"embeddable":true,"href":"https:\/\/www.taiyou-clinic.jp\/blog\/wp-json\/wp\/v2\/comments?post=2740"}],"version-history":[{"count":1,"href":"https:\/\/www.taiyou-clinic.jp\/blog\/wp-json\/wp\/v2\/posts\/2740\/revisions"}],"predecessor-version":[{"id":2741,"href":"https:\/\/www.taiyou-clinic.jp\/blog\/wp-json\/wp\/v2\/posts\/2740\/revisions\/2741"}],"wp:attachment":[{"href":"https:\/\/www.taiyou-clinic.jp\/blog\/wp-json\/wp\/v2\/media?parent=2740"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.taiyou-clinic.jp\/blog\/wp-json\/wp\/v2\/categories?post=2740"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.taiyou-clinic.jp\/blog\/wp-json\/wp\/v2\/tags?post=2740"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}