{"id":2726,"date":"2017-09-26T17:46:28","date_gmt":"2017-09-26T08:46:28","guid":{"rendered":"https:\/\/www.taiyou-clinic.jp\/blog\/?p=2726"},"modified":"2017-09-26T17:46:28","modified_gmt":"2017-09-26T08:46:28","slug":"%ef%bd%8d%ef%bd%92%ef%bd%90%e3%81%a7%e3%83%80%e3%82%a4%e3%82%a8%e3%83%83%e3%83%88","status":"publish","type":"post","link":"https:\/\/www.taiyou-clinic.jp\/blog\/archives\/2726","title":{"rendered":"\uff2d\uff32\uff30\u3067\u30c0\u30a4\u30a8\u30c3\u30c8"},"content":{"rendered":"

\u7f6e\u304d\u63db\u3048\u98df(<\/span>\u30bf\u30f3\u30d1\u30af\u8cea\u542b\u6709\u30d5\u30a9\u30fc\u30df\u30e5\u30e9\u98df)<\/span>\u306b\u3088\u308b\u80a5\u6e80\u3068\u30e1\u30bf\u30dc\u6307\u6a19\u306e\u6539\u5584\u52b9\u679c<\/p>\n

\u00a0<\/span><\/p>\n

\u30c0\u30a4\u30a8\u30c3\u30c8\u5916\u6765\u3092\u59cb\u3081\u305f\u304c\u306e\u958b\u696d\u3059\u308b\u524d\u304b\u3089\u3060\u304b\u3089\u3001\u5343\u8449\u306e\u75c5\u9662\u3067\u52e4\u52d9\u3057\u3066\u3044\u305f\u6642\u304b\u3089\u3067\u3042\u308b\u3002\u305d\u306e\u5f53\u6642\u50d5\u81ea\u8eab\u304c\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u4e09\u6627\u306e\u65e5\u3005\u3092\u9001\u3063\u3066\u3044\u3066\u3001\u7f6e\u304d\u63db\u3048\u98df\uff1d\uff2d\uff32\uff30\uff1dMeal replacement<\/span>\u3000\u3092\u3088\u304f\u98df\u3079\u3066\u3044\u305f\u3002\u5f53\u6642\u306f\uff25\uff21\uff33\u3068\u3044\u3046\u30e1\u30fc\u30ab\u30fc\u304c\u5168\u76db\u671f\u3067\u975e\u5e38\u306b\u5473\u3082\u826f\u304f\u3066\u305f\u3093\u3071\u304f\u8cea\u304c\u305f\u3063\u3077\u308a\u5165\u3063\u305f\uff2d\uff32\uff30\u304c\u58f2\u3089\u308c\u3066\u3044\u305f\u3002\u30a2\u30e1\u30ea\u30ab\u3078\u7814\u4fee\u306b\u884c\u304f\u305f\u3073\u306b\u8cfc\u5165\u3057\u3066\u5e30\u308a\u77e5\u4eba\u306b\u914d\u3063\u3066\u3044\u305f\u3002<\/p>\n

\uff2d\uff32\uff30\u306e\u30c0\u30a4\u30a8\u30c3\u30c8\u52b9\u679c\u306f\u660e\u3089\u304b\u3067\u3001\u4eca\u73fe\u5728\u306e\u30c0\u30a4\u30a8\u30c3\u30c8\u5916\u6765\u3067\u306f\u5927\u8c46\u7531\u6765\u306e\u30d7\u30ed\u30c6\u30a4\u30f3\u3092\u4f7f\u3063\u3066\u3044\u308b\u3002\u7b4b\u8089\u3092\u3064\u3051\u308b\u305f\u3081\u306b\u306f\u4e73\u6e05\uff1d\u30db\u30a8\u30a4\u30d7\u30ed\u30c6\u30a4\u30f3\u304c\u3044\u3044\u306e\u3060\u304c\u3001\u533b\u5b66\u7684\u7406\u7531\u306b\u3088\u308a\u5927\u8c46\u7531\u6765\u3092\u4f7f\u7528\u3057\u3066\u3044\u308b\u3002<\/p>\n

\u30c0\u30a4\u30a8\u30c3\u30c8\u3067\u4e00\u756a\u9593\u9055\u3063\u3066\u3044\u308b\u306e\u306f\u98df\u3079\u306a\u3044\u30c0\u30a4\u30a8\u30c3\u30c8\u3067\u3042\u308b\u304c\u3001\u305f\u3093\u3071\u304f\u8cea\u3092\u98df\u3079\u306a\u3044\u30c0\u30a4\u30a8\u30c3\u30c8\u306f\u30ea\u30d0\u30a6\u30f3\u30c9\u5fc5\u81f3\u3067\u3042\u308b\u3002\u4eca\u306f\u30cd\u30c3\u30c8\u306e\u60c5\u5831\u304c\u305f\u304f\u3055\u3093\u3042\u308b\u304c\u3001\u7406\u5c48\u901a\u308a\u306b\u3044\u304b\u306a\u3044\u306e\u3060\u304b\u3089\u3001\u305c\u3072\u5c02\u9580\u5bb6\u306e\u3068\u3053\u308d\u306b\u6765\u3066\u307b\u3057\u3044\u3002<\/p>\n

\u3061\u306a\u307f\u306b\u3001\u30e9\u30a4\u3007\u3007\u3007\u306a\u3069\u306e\u904b\u52d5\u7cfb\u3067\u7121\u7406\u3084\u308a\u75e9\u305b\u308b\u30c0\u30a4\u30a8\u30c3\u30c8\u6cd5\u306f\uff14\uff10\u6b73\u3092\u8d85\u3048\u305f\u3089\u304d\u3064\u304f\u611f\u3058\u308b\u3060\u308d\u3046\u3057\u3001\u30c0\u30a4\u30a8\u30c3\u30c8\u5f8c\u306e\u30ea\u30d0\u30a6\u30f3\u30c9\u5bfe\u7b56\u3082\u91d1\u984d\u304c\u3082\u306e\u3059\u3054\u304f\u304b\u304b\u308b\u306e\u3067\u7121\u7406\u3092\u611f\u3058\u308b\u3002<\/p>\n

\uff11\u304b\u6708\uff13\uff10\u4e07\u5186\u3082\u304b\u3051\u3066\u30e9\u30a4\u3007\u3007\u3007\u306b\u884c\u3063\u3066\u3082\u3084\u3063\u3066\u3044\u308b\u3053\u3068\u306f\uff2d\uff32\uff30\u3092\u4f7f\u3063\u305f\u98df\u4e8b\u5236\u9650\u3068\u904b\u52d5\u3067\u3042\u308b\u3002\u30c0\u30a4\u30a8\u30c3\u30c8\u5916\u6765\u3067\u3084\u3063\u3066\u3044\u308b\u4e8b\u3068\u9055\u3044\u306f\u3057\u306a\u3044\u3002\u9055\u3046\u306e\u306f\u5024\u6bb5\u3060\u3051\u3067\u3042\u308b\u3002<\/p>\n

\u00a0<\/span><\/p>\n

************************<\/span><\/p>\n

\u30a4\u30ae\u30ea\u30b9\u6804\u990a\u5b66\u4f1a\u306e\u5c02\u9580\u30b8\u30e3\u30fc\u30ca\u30eb\u306b\u3001\u80a5\u6e80\u8005\u306b\u5bfe\u3059\u308b\u30bf\u30f3\u30d1\u30af\u8cea\u542b\u6709\u30d5\u30a9\u30fc\u30df\u30e5\u30e9\u98df\uff08\u7f6e\u304d\u63db\u3048\u98df\uff09\u306e\u6e1b\u91cf\u52b9\u679c\u3068\u5fc3\u8840\u7ba1\u30ea\u30b9\u30af\u6539\u5584\u4f5c\u7528\u3092\u793a\u3057\u305f\u81e8\u5e8a\u7814\u7a76\u304c\u3001\u30a4\u30f3\u30c9\u306e\u30b0\u30eb\u30fc\u30d7\u304b\u3089\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u3057\u305f\u3002(Br J Nutr. 2017 Jun 27:1-10.)<\/span><\/p>\n

\u00a0<\/span><\/p>\n

\u80a5\u6e80\u306b\u5bfe\u3059\u308b\u98df\u4e8b\u7642\u6cd5\u3068\u3057\u3066\u3001\u30d5\u30a9\u30fc\u30df\u30e5\u30e9\u98df\u306e\u6709\u52b9\u6027\u304c\u78ba\u7acb\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n

\u80a5\u6e80\u306b\u5bfe\u3057\u3066\u7528\u3044\u3089\u308c\u308b\u30d5\u30a9\u30fc\u30df\u30e5\u30e9\u98df\u306f\u3001 \u4f4e\u30a8\u30cd\u30eb\u30ae\u30fc\u3067\u3042\u308a\u3001\u5fc5\u8981\u5341\u5206\u91cf\u306e\u305f\u3093\u3071\u304f\u8cea\u30fb\u30d3\u30bf\u30df\u30f3\u30fb\u30df\u30cd\u30e9\u30eb\u3092\u542b\u3080\u6804\u990a\u8abf\u6574\u98df\u54c1\u3067\u3059\u3002<\/p>\n

\u00a0<\/span><\/p>\n

\u5177\u4f53\u4f8b\uff1a1<\/span>\u98df\u3042\u305f\u308a200kcal<\/span>\u672a\u6e80\u3001\u305f\u3093\u3071\u304f\u8cea20<\/span>\u30b0\u30e9\u30e0\u3001 \u4f4e\u7cd6\u8cea\u30fb\u4f4e\u8102\u8cea.<\/span>\u3000\u30d3\u30bf\u30df\u30f3\u30fb\u30df\u30cd\u30e9\u30eb\u306fRDA<\/span>\u306e3<\/span>\u5206\u306e1<\/span>\uff0e \u98df\u7269\u7e4a\u7dad\u7b49\u306e\u6a5f\u80fd\u6027\u98df\u54c1\u6210\u5206\u3082.<\/span><\/p>\n

\u00a0<\/span><\/p>\n

\u5229\u7528\u4f8b\uff1a1<\/span>\u65e53<\/span>\u98df\u306e\u3046\u3061\u30011<\/span>\u98df\u3042\u308b\u3044\u306f2<\/span>\u98df\u3092\u30d5\u30a9\u30fc\u30df\u30e5\u30e9\u98df\u306b\u7f6e\u304d\u63db\u3048.<\/span><\/p>\n

\u30d5\u30a9\u30fc\u30df\u30e5\u30e9\u98df\u306f\u3001\u80a5\u6e80\u306e\u6539\u5584\u3001\u6e1b\u91cf\u3060\u3051\u3067\u306f\u306a\u304f\u3066\u3001\u30ea\u30d0\u30a6\u30f3\u30c9\u4e88\u9632\u306e\u305f\u3081\u306b\u3082\u6709\u7528\u3067\u3059\u3002<\/p>\n

\u4eca\u56de\u306e\u7814\u7a76\u3067\u306f\u3001\u30a4\u30f3\u30c9\u7cfb\u30a2\u30b8\u30a2\u4eba\u306e\u80a5\u6e80\/<\/span>\u904e\u4f53\u91cd\u306b\u5bfe\u3057\u3066\u3001<\/p>\n

\u9ad8\u30bf\u30f3\u30d1\u30af\u8cea\u542b\u6709\u30df\u30fc\u30eb\uff65\u30ea\u30d7\u30ec\u30a4\u30b9\u30e1\u30f3\u30c8(<\/span>\u7f6e\u304d\u63db\u3048\u98df)<\/span>\u306b\u3088\u308b\u3001\u4f53\u91cd\u3001\u30e1\u30bf\u30dc\u30ea\u30c3\u30af\u6307\u6a19\u3001\u8102\u8cea\u3001\u708e\u75c7\u30de\u30fc\u30ab\u30fc\u3078\u306e\u4f5c\u7528\u304c\u691c\u8a3c\u3055\u308c\u307e\u3057\u305f\u3002<\/p>\n

\u00a0<\/span><\/p>\n

\u5177\u4f53\u7684\u306b\u306f\u300112<\/span>\u9031\u9593\u306e\u30aa\u30fc\u30d7\u30f3\u30e9\u30d9\u30eb\u4e26\u884c\u7fa4\u9593\u30e9\u30f3\u30c0\u30e0\u5316\u6bd4\u8f03\u8a66\u9a13\u3068\u3057\u3066\u3001<\/p>\n

\u80a5\u6e80\/<\/span>\u904e\u4f53\u91cd\u306e\u7537\u5973122<\/span>\u540d\u3092\u5bfe\u8c61\u306b\u3001\u30fb\u30bf\u30f3\u30d1\u30af\u8cea\u542b\u6709\u7f6e\u304d\u63db\u3048\u98df\u6295\u4e0e\u7fa4\u3001\u30fb\u5bfe\u7167\u7fa4<\/p>\n

\u306e2<\/span>\u7fa4\u306b\u3064\u3044\u3066\u3001 \u4f53\u7d44\u6210\u3084\u5185\u5206\u6ccc\u4ee3\u8b1d(<\/span>\u7cd6\u30fb\u8102\u8cea\u4ee3\u8b1d)<\/span>\u6307\u6a19\u3001\u708e\u75c7\u30de\u30fc\u30ab\u30fc\u306a\u3069\u304c\u8abf\u3079\u3089\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n

\u00a0<\/span><\/p>\n

\u89e3\u6790\u306e\u7d50\u679c\u3001 \u507d\u85ac\u7fa4\u306b\u6bd4\u3079\u3066\u3001 \u9ad8\u30bf\u30f3\u30d1\u30af\u8cea\u7f6e\u304d\u63db\u3048\u98df\u306e\u6295\u4e0e\u7fa4\u3067\u306f\u3001<\/p>\n

\u4f53\u91cd\u306e\u6709\u610f\u306a\u6e1b\u5c11\u30014&#183;9 % (95 % CI 3&#183;8, 6&#183;1; P<0&#183;001)<\/span><\/p>\n

\u30a6\u30a8\u30b9\u30c8\u5468\u56f2\u5f84\u306e\u6709\u610f\u306a\u6e1b\u5c11\u30013&#183;8 % (95 % CI 2&#183;5, 5&#183;1; P<0&#183;001)<\/span><\/p>\n

\u00a0<\/span><\/p>\n

\u4f53\u8102\u80aa\u7387\u306e\u6709\u610f\u306a\u6e1b\u5c11\u30016&#183;3 % (95 % CI 4&#183;3, 8&#183;2; P<0&#183;001)<\/span><\/p>\n

\u53ce\u7e2e\u671f\u8840\u5727\u306e\u6709\u610f\u306a\u4f4e\u4e0b\u30012&#183;8 % (95 % CI 0&#183;4, 5&#183;1; P=0&#183;002)<\/span><\/p>\n

\u62e1\u5f35\u671f\u8840\u5727\u306e\u6709\u610f\u306a\u4f4e\u4e0b\u30013&#183;5 % (95 % CI 0&#183;7, 6&#183;3; P= 0&#183;01)<\/span><\/p>\n

\u30d6\u30c9\u30a6\u7cd6\u8ca0\u8377OGTT<\/span>\u5f8c\u306e\u8840\u7cd6\u5024\u306e\u6709\u610f\u306a\u4f4e\u4e0b\u3001<\/p>\n

7&#183;3 % (95 % CI 1&#183;4, 13&#183;1; P=0&#183;02)<\/span><\/p>\n

\u00a0<\/span><\/p>\n

\u7dcf\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u5024\u306e\u6709\u610f\u306a\u4f4e\u4e0b\u30012&#183;5 % (95 % CI 1&#183;6, 3&#183;5; P<0&#183;001)<\/span><\/p>\n

LDL<\/span>\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u5024\u306e\u6709\u610f\u306a\u4f4e\u4e0b\u30017&#183;3 % (95 % CI 1&#183;7, 12&#183;9; P<0&#183;01)<\/span><\/p>\n

\u00a0<\/span><\/p>\n

\u00a0<\/span><\/p>\n

ALT<\/span>\u5024\u306e\u6709\u610f\u306a\u4f4e\u4e0b\u300122&#183;0 % (95 % CI 2&#183;1, 42; P=0&#183;03) <\/span><\/p>\n

AST<\/span>\u5024\u306e\u6709\u610f\u306a\u4f4e\u4e0b\u300115&#183;2 % (95 % CI 0&#183;9, 29&#183;5; P=0&#183;04)<\/span><\/p>\n

\u304c\u898b\u51fa\u3055\u308c\u307e\u3057\u305f\u3002<\/p>\n

\u00a0<\/span><\/p>\n

\u307e\u305f\u3001 \u5bfe\u7167\u7fa4\u306b\u6bd4\u3079\u3066\u3001 \u7f6e\u304d\u63db\u3048\u98df\u6295\u4e0e\u7fa4\u3067\u306f\u3001BMI<\/span>\u306e\u6e1b\u5c11\u5e45(<\/span>\u7d76\u5bfe\u5024\u3067\u306e\u6e1b\u5c11)<\/span>\u304c0.9<\/span>\u3067\u3042\u308a\u3001 \u5bfe\u7167\u7fa4\u3068\u6bd4\u3079\u3066\u6709\u610f\u306a\u6e1b\u5c11\u3092\u793a\u3057\u307e\u305f\u3002<\/p>\n

(-0&#183;9 %, 95 % CI -1&#183;4, -0&#183;5; P<0&#183;001) <\/span><\/p>\n

\u00a0<\/span><\/p>\n

\u00a0<\/span><\/p>\n

\u8840\u4e2d\u306e\u4e2d\u6027\u8102\u80aa\u5024\u306e\u6709\u610f\u306a\u4f4e\u4e0b\u3082\u898b\u51fa\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n

11&#183;9 mg\/dl (-11&#183;9 mg\/dl, 95 % CI -21&#183;1, -2&#183;7; P<0&#183;01)<\/span><\/p>\n

\u00a0<\/span><\/p>\n

\u3055\u3089\u306b\u3001 \u7a7a\u8179\u6642\u30a4\u30f3\u30b9\u30ea\u30f3\u5024\u306e\u6709\u610f\u306a\u6e1b\u5c11\u3001(3&#183;8 v. 0 %<\/span>\u3001P=0&#183;002)<\/span><\/p>\n

OGTT<\/span>\u5f8c\u306e\u30a4\u30f3\u30b9\u30ea\u30f3\u5024\u306e\u6709\u610f\u306a\u6e1b\u5c11\u3001(50&#183;3 v. 77&#183;3 mU\/l<\/span>\u3001P=0&#183;005)<\/span><\/p>\n

hs-CRP<\/span>\u5024\u306e\u6709\u610f\u306a\u6e1b\u5c11(16&#183;7 % v. 0 %, P=0&#183;002)<\/span><\/p>\n

\u3082\u898b\u51fa\u3055\u308c\u307e\u3057\u305f\u3002<\/p>\n

\u00a0<\/span><\/p>\n

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