{"id":2379,"date":"2016-06-14T15:50:13","date_gmt":"2016-06-14T06:50:13","guid":{"rendered":"https:\/\/www.taiyou-clinic.jp\/blog\/?p=2379"},"modified":"2016-06-14T15:50:13","modified_gmt":"2016-06-14T06:50:13","slug":"%e3%83%93%e3%83%bc%e3%83%ab%e3%81%ae%e6%b6%88%e8%b2%bb%e3%81%a8%e3%82%a2%e3%83%ab%e3%83%84%e3%83%8f%e3%82%a4%e3%83%9e%e3%83%bc%e7%97%85%e3%83%aa%e3%82%b9%e3%82%af","status":"publish","type":"post","link":"https:\/\/www.taiyou-clinic.jp\/blog\/archives\/2379","title":{"rendered":"\u30d3\u30fc\u30eb\u306e\u6d88\u8cbb\u3068\u30a2\u30eb\u30c4\u30cf\u30a4\u30de\u30fc\u75c5\u30ea\u30b9\u30af"},"content":{"rendered":"<p><strong>\u00a0<\/strong><\/p>\n<p>&nbsp;<\/p>\n<p>\u30a2\u30df\u30ed\u30a4\u30c9\u305f\u3093\u3071\u304f\u8cea\u306e\u84c4\u7a4d\u306f\u591a\u304f\u306e\u75be\u60a3\u306b\u95a2\u9023\u304c\u3042\u308a\u307e\u3059\u3002\u30a2\u30eb\u30c4\u30cf\u30a4\u30de\u30fc\u578b\u8a8d\u77e5\u75c7\u3001\u2161\u578b\u7cd6\u5c3f\u75c5\u3001\u72c2\u725b\u75c5\u3001\u30cf\u30f3\u30c1\u30f3\u30c8\u30f3\u75c5\u3001\u7532\u72b6\u817a\u9ac4\u69d8\u764c\u3001\u4e0d\u6574\u8108\u306a\u3069\u3067\u3059\u3002\u3044\u305a\u308c\u3082\u3053\u306e\u30a2\u30df\u30ed\u30a4\u30c9\u305f\u3093\u3071\u304f\u304c\u4f5c\u308b\u30a2\u30df\u30ed\u30a4\u30c9\u306e\u84c4\u7a4d\u304c\u7d44\u7e54\u69cb\u9020\u3092\u7834\u58ca\u3059\u308b\u4e8b\u3067\u3042\u308a\u3001\u305d\u308c\u306b\u3088\u3063\u3066\u6b63\u5e38\u306a\u7d30\u80de\u306e\u50cd\u304d\u3092\u963b\u5bb3\u3055\u308c\u308b\u3053\u3068\u3067\u3042\u308b\u3002<\/p>\n<p>\u30d3\u30fc\u30eb\u3092\u98f2\u3080\u3053\u3068\u3067\u30a2\u30df\u30ed\u30a4\u30c9\u305f\u3093\u3071\u304f\u8cea\u306e\u84c4\u7a4d\u304c\u6291\u5236\u3055\u308c\u308b\u306a\u3089\u3070\u3001\u6cbb\u7642\u306e\u5c55\u671b\u304c\u958b\u3051\u308b\u3053\u3068\u306b\u306a\u308b\u3002\u30a2\u30eb\u30b3\u30fc\u30eb\u306e\u4e2d\u3067\u3082\u30d3\u30fc\u30eb\u3060\u3051\u3068\u3044\u3046\u306a\u3089\u672c\u5f53\u306b\u7269\u8cea\u7684\u306b\u30d3\u30fc\u30eb\u306f\u6709\u7528\u306a\u50cd\u304d\u3092\u6301\u3064\u53ef\u80fd\u6027\u304c\u3042\u308b\u3002<\/p>\n<p>&nbsp;<\/p>\n<p>******************************<\/p>\n<p><span><a href=\"http:\/\/www.dhcblog.com\/kamohara\/\">http:\/\/www.dhcblog.com\/kamohara\/<\/a><\/span><\/p>\n<p><span>\u00a0<\/span><\/p>\n<p>\u81e8\u5e8a\u30a2\u30eb\u30b3\u30fc\u30eb\u4ee3\u8b1d\u7814\u7a76\u306e\u5c02\u9580\u30b8\u30e3\u30fc\u30ca\u30eb<span>(<\/span>\u96fb\u5b50\u7248<span>)<\/span>\u306b\u3001\u30d3\u30fc\u30eb\u306e\u6442\u53d6\u304c\u591a\u3044\u3068\u3001\u8133\u5185\u306e\u30a2\u30df\u30ed\u30a4\u30c9<span>\u03b2<\/span>\u30bf\u30f3\u30d1\u30af\u8cea\u306e\u84c4\u7a4d\u304c\u5c11\u306a\u3044\u3001\u3068\u3044\u3046\u95a2\u9023\u3092\u793a\u3057\u305f\u7814\u7a76\u304c\u3001\u30b9\u30a6\u30a7\u30fc\u30c7\u30f3\u3068\u30d5\u30a3\u30f3\u30e9\u30f3\u30c9\u306e\u30b0\u30eb\u30fc\u30d7\u304b\u3089\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u3057\u305f\u3002<span>(<em>Alcohol Clin Exp Res<\/em>. 2016 May 24.) <\/span>\u30a2\u30eb\u30b3\u30fc\u30eb\u306e\u6d88\u8cbb\u3068\u3001\u8a8d\u77e5\u75c7\u3084\u8a8d\u77e5\u6a5f\u80fd\u969c\u5bb3\u306e\u767a\u75c7\u3068\u306e\u95a2\u4fc2\u306b\u3064\u3044\u3066\u306f\u3001\u8b70\u8ad6\u304c\u3042\u308a\u3001\u660e\u78ba\u306a\u7d50\u8ad6\u306f\u5f97\u3089\u308c\u3066\u3044\u307e\u305b\u3093\u3002 \u30a2\u30eb\u30c4\u30cf\u30a4\u30de\u30fc\u75c5\u3067\u306f\u3001\u8a18\u61b6\u3084\u8a00\u8a9e\u306a\u3069\u8a8d\u77e5\u6a5f\u80fd\u306e\u969c\u5bb3\u304c\u8a8d\u3081\u3089\u308c\u3001\u795e\u7d4c\u75c5\u7406\u5b66\u7684\u306b\u306f\u3001\u30bf\u30a6\u305f\u3093\u3071\u304f\u8cea\u306e\u30ea\u30f3\u9178\u5316\u3084\u30a2\u30df\u30ed\u30a4\u30c9<span>\u03b2<\/span>\u305f\u3093\u3071\u304f\u8cea<span>(\u03b2<\/span>\u30a2\u30df\u30ed\u30a4\u30c9\u30bf\u30f3\u30d1\u30af<span>)<\/span>\u306e\u84c4\u7a4d\u306a\u3069\u306e\u75c5\u614b\u304c\u691c\u51fa\u3055\u308c\u307e\u3059 \u3055\u3066\u3001\u4eca\u56de\u306e\u7814\u7a76\u3067\u306f\u3001\u5404\u7a2e\u306e\u30a2\u30eb\u30b3\u30fc\u30eb\u6442\u53d6\u3068\u3001\u8133\u5185\u306e<span>\u03b2<\/span>\u30a2\u30df\u30ed\u30a4\u30c9\u84c4\u7a4d\u3068\u306e\u95a2\u9023\u304c\u691c\u8a3c\u3055\u308c\u307e\u3057\u305f\u3002\u5177\u4f53\u7684\u306b\u306f\u3001 \u7a81\u7136\u6b7b\u75c7\u4f8b<span>125<\/span>\u4f8b<span>(35<\/span>\uff5e<span>70<\/span>\u6b73\u306e\u7537\u6027<span>) <\/span>\u306e\u5256\u691c\u6240\u898b\u304b\u3089\u3001<span>(Helsinki Sudden Death autopsy Series) <\/span>\u30a2\u30eb\u30b3\u30fc\u30eb\u306e\u6d88\u8cbb\u3001\u8133\u5185\u306e<span>\u03b2<\/span>\u30a2\u30df\u30ed\u30a4\u30c9\u84c4\u7a4d\u3001<span>ApoE<\/span>\u907a\u4f1d\u5b50\u591a\u578b<span>(<\/span>\u30a2\u30eb\u30c4\u30cf\u30a4\u30de\u30fc\u75c5\u306e\u907a\u4f1d\u7d20\u56e0<span>)<\/span>\u3068\u306e\u95a2\u9023\u304c\u8abf\u3079\u3089\u308c\u3066\u3044\u307e\u3059\u3002 \u672c\u4eba\u306e\u30a2\u30eb\u30b3\u30fc\u30eb\u306e\u6d88\u8cbb\u6b74\u306b\u95a2\u3057\u3066\u3001\u89aa\u985e\u3092\u5bfe\u8c61\u306b\u8cea\u554f\u7968\u3067\u306e\u8abf\u67fb\u304c\u884c\u308f\u308c\u3001<span>\u03b2<\/span>\u30a2\u30df\u30ed\u30a4\u30c9\u306f\u8133\u5185\u306e\u795e\u7d4c\u7d44\u7e54\u5b66\u7684\u691c\u67fb\u306b\u3088\u308b\u6e2c\u5b9a\u304c\u884c\u308f\u308c\u307e\u3057\u305f\u3002<span> ApoE<\/span>\u907a\u4f1d\u5b50\u591a\u578b\u306f\u3001\u5fc3\u7b4b\u306e\u30b5\u30f3\u30d7\u30eb\u304b\u3089<span>DNA<\/span>\u62bd\u51fa\u306b\u3088\u308a\u8abf\u3079\u3089\u308c\u3066\u3044\u307e\u3059\u3002 \u89e3\u6790\u306e\u7d50\u679c\u3001\u307e\u305a\u3001\u8133\u5185\u306e<span>\u03b2<\/span>\u30a2\u30df\u30ed\u30a4\u30c9\u84c4\u7a4d\u306e\u5897\u5927\u306f\u3001\u52a0\u9f62\u3068\u306e\u6709\u610f\u306a\u76f8\u95a2\u304c\u898b\u51fa\u3055\u308c\u307e\u3057\u305f\u3002<span>(p = 0.001; OR = 1.09, CI = 1.04 to 1.15) <\/span>\u6b21\u306b\u3001\u30d3\u30fc\u30eb\u306e\u6d88\u8cbb\u306f\u3001\u8133\u5185\u306e<span>\u03b2<\/span>\u30a2\u30df\u30ed\u30a4\u30c9\u84c4\u7a4d\u306e\u6e1b\u5c11\u3068\u6709\u610f\u306a\u76f8\u95a2\u304c\u898b\u51fa\u3055\u308c\u305f\u3068\u3044\u3046\u3053\u3068\u3067\u3059\u3002<span>(p = 0.024; OR = 0.35, CI = 0.14 to 0.87) <\/span>\u306a\u304a\u3001\u30a2\u30eb\u30b3\u30fc\u30eb\u306e\u6d88\u8cbb\u91cf\u3068\u3001<span>\u03b2<\/span>\u30a2\u30df\u30ed\u30a4\u30c9\u84c4\u7a4d\u306f\u95a2\u9023\u304c\u306a\u304f\u3001\u307e\u305f\u3001\u84b8\u7559\u9152\u3084\u30ef\u30a4\u30f3\u306e\u6d88\u8cbb\u3082\u95a2\u9023\u306f\u8a8d\u3081\u3089\u308c\u307e\u305b\u3093\u3067\u3057\u305f\u3002 \u4ee5\u4e0a\u306e\u30c7\u30fc\u30bf\u304b\u3089\u3001\u8ad6\u6587\u8457\u8005\u3089\u306f\u3001\u30d3\u30fc\u30eb\u6d88\u8cbb\u306b\u3088\u308a\u3001\u8133\u5185\u3067\u306e<span>\u03b2<\/span>\u30a2\u30df\u30ed\u30a4\u30c9\u84c4\u7a4d\u304c\u6291\u5236\u3055\u308c\u308b\u53ef\u80fd\u6027\u3092\u8003\u5bdf\u3057\u3066\u3044\u307e\u3059\u3002 \u4eca\u5f8c\u3001\u56e0\u679c\u95a2\u4fc2\u3084\u4f5c\u7528\u6a5f\u5e8f\u306e\u691c\u8a3c\u3001\u81e8\u5e8a\u7684\u610f\u7fa9\u306e\u89e3\u6790\u304c\u671f\u5f85\u3055\u308c\u308b\u5206\u91ce\u3067\u3059\u3002 \u73fe\u6642\u70b9\u3067\u306f\u3001\u3055\u3059\u304c\u306b\u3001\u30d3\u30fc\u30eb\u3092\u98f2\u3081\u3070\u30a2\u30eb\u30c4\u30cf\u30a4\u30de\u30fc\u75c5\u30ea\u30b9\u30af\u304c\u4f4e\u4e0b\u3059\u308b\u3068\u306f\u307e\u3060\u307e\u3060\u8a00\u3048\u306a\u3044\u3067\u3059\u306e\u3067\u3001\u95a2\u4e0e\u3059\u308b\u6a5f\u80fd\u6027\u98df\u54c1\u6210\u5206\u306e\u89e3\u6790\u3084\u4f5c\u7528\u30e1\u30ab\u30cb\u30ba\u30e0\u306e\u691c\u8a3c\u3001\u305d\u306e\u4ed6\u3001\u65e5\u672c\u4eba\u3067\u306e\u691c\u8a3c\u306a\u3069\u304c\u5fc5\u8981\u3067\u3059\u3002<span> (<\/span>\u4eca\u56de\u306f\u3001\u5256\u691c\u6240\u898b\u306b\u3088\u308b\u8133\u5185<span>\u03b2<\/span>\u30a2\u30df\u30ed\u30a4\u30c9\u84c4\u7a4d\u306f\u5b9a\u91cf\u7684\u306b\u8abf\u3079\u3089\u308c\u3066\u3044\u307e\u3059\u304c\u3001\u98f2\u9152\u91cf\u306f\u3001\u672c\u4eba\u3067\u306f\u306a\u304f\u3001\u89aa\u985e\u304b\u3089\u306e\u8cea\u554f\u7968\u306e\u7d50\u679c\u3067\u3059\u306e\u3067\u3001\u4fe1\u983c\u5ea6\u304c\u5fc5\u305a\u3057\u3082\u9ad8\u3044\u308f\u3051\u3067\u306f\u306a\u304f\u3001\u4eba\u7a2e\u5dee\u3082\u3042\u308b\u3068\u601d\u308f\u308c\u307e\u3059\u3002<span>)<\/span><\/p>\n<p><span>\u00a0<\/span><\/p>\n<p><span>\u00a0<\/span><\/p>\n<p><span>\u00a0<\/span><\/p>\n<p><span>\u00a0<\/span><\/p>\n<p><span>\u00a0<\/span><\/p>\n<p><span>\u00a0<\/span><\/p>\n<p><span>\u00a0<\/span><\/p>\n<p><span>\u00a0<\/span><\/p>\n<p><span>\u00a0<\/span><\/p>\n<p><span>\u00a0<\/span><\/p>\n<p><span>\u00a0<\/span><\/p>\n<p><span>\u00a0<\/span><\/p>\n<p><span>\u00a0<\/span><\/p>\n<p><span>\u00a0<\/span><\/p>\n<p><span>\u00a0<\/span><\/p>\n<p><span>\u00a0<\/span><\/p>\n<p><span>\u00a0<\/span><\/p>\n<p><span>\u00a0<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u00a0 &nbsp; \u30a2\u30df\u30ed\u30a4\u30c9\u305f\u3093\u3071\u304f\u8cea\u306e\u84c4\u7a4d\u306f\u591a\u304f\u306e\u75be\u60a3\u306b\u95a2\u9023\u304c\u3042\u308a\u307e\u3059\u3002\u30a2\u30eb\u30c4\u30cf\u30a4\u30de\u30fc\u578b\u8a8d\u77e5\u75c7\u3001\u2161\u578b\u7cd6\u5c3f\u75c5\u3001\u72c2\u725b\u75c5\u3001\u30cf\u30f3\u30c1\u30f3\u30c8\u30f3\u75c5\u3001\u7532\u72b6\u817a\u9ac4\u69d8\u764c\u3001\u4e0d\u6574\u8108\u306a\u3069\u3067\u3059\u3002\u3044\u305a\u308c\u3082\u3053\u306e\u30a2\u30df\u30ed\u30a4\u30c9\u305f\u3093\u3071\u304f\u304c\u4f5c\u308b\u30a2\u30df\u30ed\u30a4\u30c9\u306e\u84c4\u7a4d\u304c\u7d44 [&hellip;]<\/p>\n","protected":false},"author":6,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[4],"tags":[],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/www.taiyou-clinic.jp\/blog\/wp-json\/wp\/v2\/posts\/2379"}],"collection":[{"href":"https:\/\/www.taiyou-clinic.jp\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.taiyou-clinic.jp\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.taiyou-clinic.jp\/blog\/wp-json\/wp\/v2\/users\/6"}],"replies":[{"embeddable":true,"href":"https:\/\/www.taiyou-clinic.jp\/blog\/wp-json\/wp\/v2\/comments?post=2379"}],"version-history":[{"count":1,"href":"https:\/\/www.taiyou-clinic.jp\/blog\/wp-json\/wp\/v2\/posts\/2379\/revisions"}],"predecessor-version":[{"id":2380,"href":"https:\/\/www.taiyou-clinic.jp\/blog\/wp-json\/wp\/v2\/posts\/2379\/revisions\/2380"}],"wp:attachment":[{"href":"https:\/\/www.taiyou-clinic.jp\/blog\/wp-json\/wp\/v2\/media?parent=2379"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.taiyou-clinic.jp\/blog\/wp-json\/wp\/v2\/categories?post=2379"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.taiyou-clinic.jp\/blog\/wp-json\/wp\/v2\/tags?post=2379"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}