{"id":2266,"date":"2015-12-09T10:25:55","date_gmt":"2015-12-09T01:25:55","guid":{"rendered":"https:\/\/www.taiyou-clinic.jp\/blog\/?p=2266"},"modified":"2019-02-18T11:00:31","modified_gmt":"2019-02-18T02:00:31","slug":"%e3%82%b3%e3%82%a8%e3%83%b3%e3%82%b6%e3%82%a4%e3%83%a0q10%e3%82%bb%e3%83%ac%e3%83%b3%e3%81%ab%e3%82%88%e3%82%8b%e9%ab%98%e9%bd%a2%e8%80%85%e3%81%ae%e5%bf%83%e8%87%93%e7%97%85%e6%ad%bb%e4%ba%a1","status":"publish","type":"post","link":"https:\/\/www.taiyou-clinic.jp\/blog\/archives\/2266","title":{"rendered":"\u30b3\u30a8\u30f3\u30b6\u30a4\u30e0Q10+\u30bb\u30ec\u30f3\u306b\u3088\u308b\u9ad8\u9f62\u8005\u306e\u5fc3\u81d3\u75c5\u6b7b\u4ea1\u7387\u4f4e\u4e0b\u52b9\u679c\u3000"},"content":{"rendered":"

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\u4eca\u6708\u306e\u79d1\u5b66\u8a8c\u30d7\u30ed\u30b9\u30ef\u30f3\u306b\u3001\u30b3\u30a8\u30f3\u30b6\u30a4\u30e0Q10+\u30bb\u30ec\u30f3\u30b5\u30d7\u30ea\u30e1\u30f3\u30c8\u306b\u3088\u308b\u9ad8\u9f62\u8005\u306e\u6b7b\u4ea1\u7387\u3078\u306e\u5f71\u97ff\u3092\u691c\u8a3c\u3057\u305f\u81e8\u5e8a\u7814\u7a76\u304c\u3001\u5317\u6b27\u306e\u30b0\u30eb\u30fc\u30d7\u304b\u3089\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u3057\u305f\u3002 (PLoS One. 2015 Dec 1;10(12):e0141641.) \u30b3\u30a8\u30f3\u30b6\u30a4\u30e0Q10\u306f\u3001\u6297\u9178\u5316\u4f5c\u7528\u3084ATP\u7523\u751f\u4f5c\u7528\u3092\u6709\u3059\u308b\u6a5f\u80fd\u6027\u6210\u5206\u3067\u3001\u4f53\u5185\u3067\u3082\u7523\u751f\u3055\u308c\u307e\u3059\u3002 \u3057\u304b\u3057\u3001\u52a0\u9f62\u3068\u3068\u3082\u306b\u5185\u5728\u6027\u30b3\u30a8\u30f3\u30b6\u30a4\u30e0Q10\u306f\u6e1b\u5c11\u3057\u3001\u751f\u6d3b\u7fd2\u6163\u75c5\u3084\u6162\u6027\u75be\u60a3\u3067\u3082\u4f4e\u4e0b\u304c\u307f\u3089\u308c\u308b\u3053\u3068\u304b\u3089\u3001\u30a2\u30f3\u30c1\u30a8\u30a4\u30b8\u30f3\u30b0\u5206\u91ce\u3067\u5e83\u304f\u6442\u53d6\u304c\u63a8\u5968\u3055\u308c\u3066\u3044\u308b\u30d9\u30fc\u30b7\u30c3\u30af\u30b5\u30d7\u30ea\u30e1\u30f3\u30c8\u3067\u3059\u3002 \u30bb\u30ec\u30f3\u306f\u3001\u6297\u9178\u5316\u4f5c\u7528\u3092\u6709\u3059\u308b\u5fc5\u9808\u30df\u30cd\u30e9\u30eb\u306e1\u7a2e\u3067\u3059\u3002 \u4eca\u56de\u306e\u7814\u7a76\u306f\u3001\u30b3\u30a8\u30f3\u30b6\u30a4\u30e0Q10\u3068\u30bb\u30ec\u30f3\u306e\u30b5\u30d7\u30ea\u30e1\u30f3\u30c8\u30924\u5e74\u9593\u6295\u4e0e\u3057\u305f\u81e8\u5e8a\u7814\u7a76\u306e\u8ffd\u8de1\u8abf\u67fb\u3067\u3059\u3002 \u5148\u884c\u7814\u7a76\u3067\u306f\u3001\u9ad8\u9f62\u8005443\u540d\u3092\u5bfe\u8c61\u306b\u3001 \u30b3\u30a8\u30f3\u30b6\u30a4\u30e0Q10+\u30bb\u30ec\u30f3\u6295\u4e0e\u306b\u3088\u308a\u3001\u5fc3\u8840\u7ba1\u75be\u60a3\u306b\u3088\u308b\u6b7b\u4ea1\u7387\u306e\u4f4e\u4e0b\u304c\u8a8d\u3081\u3089\u308c\u307e\u3057\u305f\u3002 \u6295\u4e0e\u3055\u308c\u305f\u30b5\u30d7\u30ea\u30e1\u30f3\u30c8\u306f\u30011\u65e5\u3042\u305f\u308a200mg\u306e\u30b3\u30a8\u30f3\u30b6\u30a4\u30e0Q10\u3001200\u30de\u30a4\u30af\u30ed\u30b0\u30e9\u30e0\u306e\u30bb\u30ec\u30f3 \u3067\u3059\u3002 \u4eca\u56de\u306f\u3001\u30b9\u30a6\u30a7\u30fc\u30c7\u30f3\u306b\u5728\u4f4f\u306e\u5065\u5eb7\u306a\u9ad8\u9f62\u8005443\u540d\u3092\u5bfe\u8c61\u306b\u3001\u30b5\u30d7\u30ea\u30e1\u30f3\u30c8\u6295\u4e0e\u5f8c\u306e10\u5e74\u9593\u306b\u308f\u305f\u308b\u8ffd\u8de1\u8abf\u67fb\u304c\u884c\u308f\u308c\u3001\u5fc3\u8840\u7ba1\u75be\u60a3\u306e\u6b7b\u4ea1\u7387\u304c\u8abf\u3079\u3089\u308c\u3066\u3044\u307e\u3059\u3002 \u5fc3\u8840\u7ba1\u75be\u60a3\u306b\u95a2\u3059\u308b\u8ffd\u8de1\u671f\u9593\u306e\u4e2d\u592e\u5024\u306f\u30013668\u65e5 (range 348&#8211;4488\u65e5)\u3001\u3064\u307e\u308a\u7d0410\u5e74\u9593\u3067\u3057\u305f\u3002 \u751f\u5b58\u8005\u306e\u30b0\u30eb\u30fc\u30d7\u3067\u306f\u30013836 \u65e5(range 689&#8211;4488), \u975e\u751f\u5b58\u8005\u30b0\u30eb\u30fc\u30d7\u3067\u306f\u30012505 \u65e5(range 348&#8211;4347) \u3067\u3057\u305f\u3002 \u89e3\u6790\u306e\u7d50\u679c\u3001\u30b3\u30a8\u30f3\u30b6\u30a4\u30e0Q10+\u30bb\u30ec\u30f3\u6295\u4e0e\u306b\u3088\u308a\u3001\u5fc3\u8840\u7ba1\u75be\u60a3\u306b\u3088\u308b\u6b7b\u4ea1\u7387\u306e\u6709\u610f\u306a\u6e1b\u5c11\u304c\u8a8d\u3081\u3089\u308c\u305f\u3068\u3044\u3046\u3053\u3068\u3067\u3059\u3002(49\uff05\u306e\u4f4e\u4e0b\uff1aHR: 0.51; 95%CI 0.36-0.74; P = 0.0003) 4\u5e74\u9593\u306e\u4ecb\u5165\u5f8c\u306e10\u5e74\u9593\u306e\u30d5\u30a9\u30ed\u30fc\u30a2\u30c3\u30d7\u671f\u9593\u306b\u304a\u3044\u3066\u3001\u30b3\u30a8\u30f3\u30b6\u30a4\u30e0Q10+\u30bb\u30ec\u30f3\u306b\u3088\u308b\u5fc3\u8840\u7ba1\u30ea\u30b9\u30af\u4f4e\u4e0b\u52b9\u679c\u306f\u7d99\u7d9a\u3057\u3066\u8a8d\u3081\u3089\u308c\u305f\u3068\u3044\u3046\u3053\u3068\u3067\u3059\u3002 \u307e\u305f\u3001\u3053\u306e\u52b9\u679c\u306f\u3001\u7537\u5973\u5171\u306b\u793a\u3055\u308c\u3066\u3044\u307e\u3059\u3002 \u865a\u8840\u6027\u5fc3\u75be\u60a3\u306b\u5bfe\u3059\u308b\u30ea\u30b9\u30af\u4f4e\u6e1b\u52b9\u679c\u3082\u540c\u69d8\u306b\u8a8d\u3081\u3089\u308c\u307e\u3057\u305f\u3002 (49\uff05\u306e\u30ea\u30b9\u30af\u4f4e\u4e0b\uff1aHR: 0.51; 95%CI 0.27-0.97; P = 0.04) \u4ee5\u4e0a\u306e\u30c7\u30fc\u30bf\u304b\u3089\u3001\u5730\u57df\u5c45\u4f4f\u306e\u5065\u5eb7\u306a\u9ad8\u9f62\u8005\u306b\u304a\u3044\u3066\u3001\u30b3\u30a8\u30f3\u30b6\u30a4\u30e0Q10+\u30bb\u30ec\u30f3\u306e\u30b5\u30d7\u30ea\u30e1\u30f3\u30c8\u30924\u5e74\u9593\u6295\u4e0e\u3059\u308b\u3053\u3068\u3067\u3001\u305d\u306e\u5f8c\u3082\u7d99\u7d9a\u3057\u3066\u3001\u5fc3\u8840\u7ba1\u75be\u60a3\u30ea\u30b9\u30af\u306e\u6709\u610f\u306a\u4f4e\u4e0b\u52b9\u679c\u304c\u793a\u5506\u3055\u308c\u307e\u3059\u3002 \u30b3\u30a8\u30f3\u30b6\u30a4\u30e0Q10\u306f\u3001\u6297\u9178\u5316\u4f5c\u7528\u3084ATP\u7523\u751f\u4f5c\u7528\u3092\u6709\u3059\u308b\u6a5f\u80fd\u6027\u6210\u5206\u3067\u3001\u4f53\u5185\u3067\u3082\u7523\u751f\u3055\u308c\u307e\u3059\u3002 \u3057\u304b\u3057\u3001\u52a0\u9f62\u3068\u3068\u3082\u306b\u5185\u5728\u6027\u30b3\u30a8\u30f3\u30b6\u30a4\u30e0Q10\u306f\u6e1b\u5c11\u3057\u3001\u751f\u6d3b\u7fd2\u6163\u75c5\u3084\u6162\u6027\u75be\u60a3\u3067\u3082\u4f4e\u4e0b\u304c\u307f\u3089\u308c\u308b\u3053\u3068\u304b\u3089\u3001\u30a2\u30f3\u30c1\u30a8\u30a4\u30b8\u30f3\u30b0\u5206\u91ce\u3067\u5e83\u304f\u6442\u53d6\u304c\u63a8\u5968\u3055\u308c\u3066\u3044\u308b\u30d9\u30fc\u30b7\u30c3\u30af\u30b5\u30d7\u30ea\u30e1\u30f3\u30c8\u3067\u3059\u3002 \u65e5\u672c\u3067\u306f\u3001\u6570\u5341\u5e74\u524d\u306b\u3001\u539a\u751f\u7701(\u5f53\u6642)\u306b\u3088\u308a\u3001\u5fc3\u4e0d\u5168\u306e\u6cbb\u7642\u85ac\u3068\u3057\u3066\u8a8d\u53ef\u3055\u308c\u3066\u3044\u307e\u3059\u304c\u30011\u65e5\u7528\u91cf\u304c30mg\u3068\u5c11\u306a\u304f\u3001\u65e5\u672c\u306e\u81e8\u5e8a\u73fe\u5834\u3067\u306f\u3001\u30b3\u30a8\u30f3\u30b6\u30a4\u30e0Q10\u306f\u52b9\u679c\u3092\u5b9f\u611f\u3057\u306a\u3044\u3001\u3068\u3044\u3063\u305f\u2019\u98a8\u8a55\u88ab\u5bb3\u2019\u306b\u306a\u3063\u3066\u3044\u307e\u3059\u3002\u4e00\u822c\u306b\u3001\u30a2\u30f3\u30c1\u30a8\u30a4\u30b8\u30f3\u30b0\u30fb\u5065\u5eb7\u5897\u9032\u30fb\u75be\u75c5\u4e88\u9632\u306e\u76ee\u7684\u3067\u306f\u30011\u65e5\u3042\u305f\u308a90mg\u304b\u3089100mg\u524d\u5f8c\u3001 \u307e\u305f\u3001\u5fc3\u8840\u7ba1\u75be\u60a3\u3084\u751f\u6d3b\u7fd2\u6163\u75c5\u306e\u6cbb\u7642\uff08\u88dc\u5b8c\u7642\u6cd5\uff09\u76ee\u7684\u3067\u306f\u3001 1\u65e5\u3042\u305f\u308a200mg\uff5e300mg\u3068\u3044\u3063\u305f\u7528\u91cf\u3068\u306a\u308a\u307e\u3059\u3002 \u30b3\u30a8\u30f3\u30b6\u30a4\u30e0<\/span>Q10<\/a>\u306b\u306f\u3001\u9178\u5316\u578b(=\u30e6\u30d3\u30ad\u30ce\u30f3\uff0cubiquinone)\u3068\u9084\u5143\u578b(=\u30e6\u30d3\u30ad\u30ce\u30fc\u30eb\uff0cubiquinol)\u304c\u3042\u308a\u307e\u3059\u3002 \u9084\u5143\u578bCoQ10\u306e\u307b\u3046\u304c\u3001\u9178\u5316\u578bCoQ10\u3088\u308a\u3082\u4f53\u5185\u3067\u5229\u7528\u3055\u308c\u3084\u3059\u3044\u3068\u8003\u3048\u3089\u308c\u307e\u3059\u3002 \uff08\u9178\u5316\u578bCoQ10\u306f\u3001\u4f53\u5185\u306b\u5438\u53ce\u3055\u308c\u305f\u5f8c\u3001\u3044\u3063\u305f\u3093\u9084\u5143\u3055\u308c\u3066\u304b\u3089\u3001\u5229\u7528\u3055\u308c\u307e\u3059\u3002\uff09 \u30b3\u30a8\u30f3\u30b6\u30a4\u30e0Q10\u306b\u95a2\u3059\u308b\u3053\u308c\u307e\u3067\u306e\u7814\u7a76\u306e\u591a\u304f\u306f\u3001\u9178\u5316\u578b(=\u30e6\u30d3\u30ad\u30ce\u30f3\uff0cubiquinone)\u3092\u7528\u3044\u3066\u3044\u307e\u3059\u3002\u3057\u305f\u304c\u3063\u3066\u3001\u4e00\u822c\u7684\u306b\u306f\u3001\u751f\u6d3b\u7fd2\u6163\u75c5\u306e\u4e88\u9632\u3084\u30a2\u30f3\u30c1\u30a8\u30a4\u30b8\u30f3\u30b0\u76ee\u7684\u306b\u95a2\u3057\u3066\u3001\u9178\u5316\u578b<\/span>CoQ10<\/a>\u306e\u30e6\u30d3\u30ad\u30ce\u30f3\u306e\u6442\u53d6\u3067\u5341\u5206\u306a\u52b9\u679c\u304c\u671f\u5f85\u3067\u304d\u307e\u3059\u3002 \u4e00\u65b9\u3001\u7279\u5b9a\u306e\u75be\u60a3\u306b\u5bfe\u3057\u3066\u7528\u3044\u308b\u5834\u5408\u3001\u3042\u308b\u3044\u306f\u3001\u4f53\u5185\u306e\u751f\u7406\u6a5f\u80fd\u304c\u4f4e\u4e0b\u3057\u3066\u3044\u308b\u9ad8\u9f62\u8005\u306e\u5834\u5408\u306b\u306f\u3001\u9084\u5143\u578b<\/span>CoQ10<\/a>\u306e\u5229\u7528\u304c\u63a8\u5968\u3055\u308c\u307e\u3059\u3002<\/p>\n","protected":false},"excerpt":{"rendered":"

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