{"id":2062,"date":"2015-01-27T18:01:02","date_gmt":"2015-01-27T09:01:02","guid":{"rendered":"https:\/\/www.taiyou-clinic.jp\/blog\/?p=2062"},"modified":"2015-01-27T18:01:02","modified_gmt":"2015-01-27T09:01:02","slug":"%e3%83%9e%e3%83%ab%e3%83%81%e3%83%93%e3%82%bf%e3%83%9f%e3%83%b3%e3%83%bb%e3%83%9e%e3%83%ab%e3%83%81%e3%83%9f%e3%83%8d%e3%83%a9%e3%83%ab%e3%82%b5%e3%83%97%e3%83%aa%e3%83%a1%e3%83%b3%e3%83%88%e3%81%ab","status":"publish","type":"post","link":"https:\/\/www.taiyou-clinic.jp\/blog\/archives\/2062","title":{"rendered":"\u30de\u30eb\u30c1\u30d3\u30bf\u30df\u30f3\u30fb\u30de\u30eb\u30c1\u30df\u30cd\u30e9\u30eb\u30b5\u30d7\u30ea\u30e1\u30f3\u30c8\u306b\u3088\u308b\u304c\u3093\u4e88\u9632"},"content":{"rendered":"<p><strong>\u00a0<\/strong><\/p>\n<p>\u30de\u30eb\u30c1\u30d3\u30bf\u30df\u30f3\u30df\u30cd\u30e9\u30eb\u306f\u304c\u3093\u4e88\u9632\u306b\u5f79\u7acb\u3064\u3068\u3044\u3046\u7814\u7a76\u3067\u3059\u30021993\u5e74\u306b\u306f\u30d3\u30bf\u30df\u30f3\u30df\u30cd\u30e9\u30eb\u306e\u9ad8\u5bb9\u91cf\u6295\u4e0e\u3067\u672b\u671f\u304c\u3093\u60a3\u8005\u304c\u512a\u4f4d\u306b\u4f59\u547d\u304c\u5ef6\u9577\u3057\u305f\u3068\u3044\u3046\u7814\u7a76\u5831\u544a\u3082\u3042\u308a\u307e\u3059\u3002\u8eab\u8fd1\u306b\u3042\u308b\u6804\u990a\u7d20\u3067\u3059\u304c\u3001\u3046\u307e\u304f\u6442\u53d6\u3059\u308c\u3070\u6297\u304c\u3093\u4f5c\u7528\u3001\u304c\u3093\u4e88\u9632\u4f5c\u7528\u3082\u3042\u308b\u306e\u3067\u305c\u3072\u3046\u307e\u304f\u5229\u7528\u3057\u305f\u3044\u3082\u306e\u3067\u3059\u3002<\/p>\n<p>&nbsp;<\/p>\n<p>**********************************<\/p>\n<p>http:\/\/www.dhcblog.com\/kamohara\/<\/p>\n<p>\u4eca\u6708\u306e\u81e8\u5e8a\u533b\u5b66\u306e\u5c02\u9580\u30b8\u30e3\u30fc\u30ca\u30eb\u306b\u3001\u30d7\u30e9\u30a4\u30de\u30ea\u30b1\u30a2\u306b\u304a\u3051\u308b\u30de\u30eb\u30c1\u30d3\u30bf\u30df\u30f3\u30fb\u30de\u30eb\u30c1\u30df\u30cd\u30e9\u30eb\u30b5\u30d7\u30ea\u30e1\u30f3\u30c8\u306e\u304c\u3093\u4e88\u9632\u306b\u95a2\u3059\u308b\u30ec\u30d3\u30e5\u30fc\u304c\u3001\u7c73\u56fd\u306e\u30b0\u30eb\u30fc\u30d7\u304b\u3089\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u3057\u305f\u3002 (<em>Postgrad Med. <\/em>2015 Jan;127(1):107-16) \u30de\u30eb\u30c1\u30d3\u30bf\u30df\u30f3\u30fb\u30de\u30eb\u30c1\u30df\u30cd\u30e9\u30eb\u30b5\u30d7\u30ea\u30e1\u30f3\u30c8\u306f\u3001\u666e\u6bb5\u306e\u98df\u751f\u6d3b\u3060\u3051\u3067\u306f\u4e0d\u8db3\u3057\u304c\u3061\u306a\u5fc5\u9808\u6804\u990a\u7d20\u3092\u5ff5\u306e\u305f\u3081\u306b\u6442\u308b\u3001\u3068\u3044\u3046\u4fdd\u967a\u7684\u306a\u610f\u5473\u5408\u3044\u306b\u52a0\u3048\u3066\u3001\u304c\u3093\u306a\u3069\u306e\u751f\u6d3b\u7fd2\u6163\u75c5\u3084\u6162\u6027\u75be\u60a3\u306e\u30ea\u30b9\u30af\u4f4e\u6e1b\u3082\u793a\u5506\u3055\u308c\u3066\u3044\u307e\u3059\u3002 \u4eca\u56de\u306e\u30ec\u30d3\u30e5\u30fc\u3067\u306f\u3001\u30de\u30eb\u30c1\u30d3\u30bf\u30df\u30f3\u30b5\u30d7\u30ea\u30e1\u30f3\u30c8\u3042\u308b\u3044\u306f\u30de\u30eb\u30c1\u30d3\u30bf\u30df\u30f3\u30de\u30eb\u30c1\u30df\u30cd\u30e9\u30eb\u30b5\u30d7\u30ea\u30e1\u30f3\u30c8\u306e\u3001\u304c\u3093\u4e88\u9632(\u304c\u3093\u30ea\u30b9\u30af\u4f4e\u6e1b\u4f5c\u7528)\u306b\u3064\u3044\u3066\u3001\u30e9\u30f3\u30c0\u30e0\u5316\u6bd4\u8f03\u8a66\u9a13\u3067\u306e\u30a8\u30d3\u30c7\u30f3\u30b9\u304c\u691c\u8a3c\u3055\u308c\u307e\u3057\u305f\u3002 \u5177\u4f53\u7684\u306b\u306f\u3001\u7c73\u56fd\u3067\u533b\u5e2b\u3092\u5bfe\u8c61\u306b\u884c\u308f\u308c\u305f\u3001\u300cPhysicians' Health Study II (PHS II)\u300d\u306b\u3064\u3044\u3066\u3067\u3059\u3002<br \/>\nPHS\u2161\u306f\u3001\u4e2d\u9ad8\u5e74\u306e\u7537\u6027\u533b\u5e2b(\u5e73\u5747\u5e74\u9f6264\u6b73)\u3092\u5bfe\u8c61\u306b\u3001\u30de\u30eb\u30c1\u30d3\u30bf\u30df\u30f3\u30de\u30eb\u30c1\u30df\u30cd\u30e9\u30eb\u30b5\u30d7\u30ea\u30e1\u30f3\u30c8\u3092\u5e73\u574711\u5e74\u9593\u6295\u4e0e\u3057\u305f\u30e9\u30f3\u30c0\u30e0\u5316\u6bd4\u8f03\u8a66\u9a13\u3067\u3059\u3002 (\u3053\u306e\u7814\u7a76\u306b\u3064\u3044\u3066\u306f\u3001JAMA\u3078\u306e\u767a\u8868\u6642\u306b\u3001\u3053\u306e\u304a\u52c9\u5f37\u30d6\u30ed\u30b0\u3067\u3082\u3001<a href=\"http:\/\/www.dhcblog.com\/kamohara\/archive\/2344\" class=\"broken_link\" rel=\"nofollow\">\u30de\u30eb\u30c1\u30d3\u30bf\u30df\u30f3\u306b\u3088\u308b\u304c\u3093\u30ea\u30b9\u30af\u4f4e\u6e1b\u52b9\u679c<\/a>\u3068\u3057\u3066\u53d6\u308a\u4e0a\u3052\u3066\u3044\u307e\u3059\u3002\uff09 \u89e3\u6790\u306e\u7d50\u679c\u3001\u30de\u30eb\u30c1\u30d3\u30bf\u30df\u30f3\u30de\u30eb\u30c1\u30df\u30cd\u30e9\u30eb\u30b5\u30d7\u30ea\u30e1\u30f3\u30c8\u6442\u53d6\u7fa4\u3067\u306f\u3001\u5168\u304c\u3093\u7f79\u60a3\u7387(\u3042\u3089\u3086\u308b\u304c\u3093\u306e\u767a\u751f\u7387)\u304c8\uff05\u6709\u610f\u306b\u4f4e\u3044\u3068\u3044\u3046\u30c7\u30fc\u30bf\u304c\u898b\u51fa\u3055\u308c\u3066\u3044\u307e\u3059\u3002(HR: 0.92; 95% CI: 0.86-0.998; p = 0.04) \u30b5\u30d6\u89e3\u6790\u3067\u306f\u3001\u304c\u3093\u306e\u65e2\u5f80\u304c\u3042\u308b\u7fa4\u306b\u304a\u3044\u3066\u9855\u8457\u306a\u52b9\u679c\u304c\u898b\u51fa\u3055\u308c\u3066\u304a\u308a\u3001\u30de\u30eb\u30c1\u30d3\u30bf\u30df\u30f3\u30df\u30cd\u30e9\u30eb\u30b5\u30d7\u30ea\u30e1\u30f3\u30c8\u306e\u6442\u53d6\u306b\u3088\u308a27\uff05\u306e\u30ea\u30b9\u30af\u4f4e\u4e0b\u3067\u3057\u305f\u3002(HR: 0.73; 95% CI: 0.56-0.96; p = 0.02) \u8ad6\u6587\u8457\u8005\u3089\u306b\u3088\u308b\u3068\u3001PHS II\u30c7\u30fc\u30bf\u306b\u57fa\u3065\u3044\u305f\u8a66\u7b97\u3067\u306f\u3001\u30de\u30eb\u30c1\u30d3\u30bf\u30df\u30f3\u30de\u30eb\u30c1\u30df\u30cd\u30e9\u30eb\u30b5\u30d7\u30ea\u30e1\u30f3\u30c8\u306e\u6442\u53d6\u306b\u3088\u308a\u3001\u5e74\u9593\u7d0468,000\u540d\u306e\u304c\u3093\u4e88\u9632(\u4e00\u6b21\u4e88\u9632)\u304c\u671f\u5f85\u3067\u304d\u3001\u4e8c\u6b21\u4e88\u9632\u3067\u306f\u3055\u3089\u306b\u5927\u304d\u3044\u52b9\u679c\u304c\u671f\u5f85\u3055\u308c\u308b\u3001\u3068\u8003\u3048\u3089\u308c\u307e\u3059\u3002 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\u30d3\u30bf\u30df\u30f3C\u3084\u30d3\u30bf\u30df\u30f3E\u3001\u30bb\u30ec\u30f3\u3068\u3044\u3063\u305f\u6297\u9178\u5316\u4f5c\u7528\u3092\u6301\u3064\u6210\u5206\u304c\u3001\u9178\u5316\u969c\u5bb3\u306e\u6291\u5236\u3092\u4ecb\u3057\u3066\u3001\u6297\u304c\u3093\u4f5c\u7528\u304a\u3088\u3073\u751f\u6d3b\u7fd2\u6163\u75c5\u4e88\u9632\u52b9\u679c\u3092\u793a\u3059\u3001\u3068\u306a\u308a\u307e\u3059\u3002) \u30de\u30eb\u30c1\u30d3\u30bf\u30df\u30f3\u30b5\u30d7\u30ea\u30e1\u30f3\u30c8\u3068\u304c\u3093\u306b\u95a2\u3057\u3066\u300150\u6b73\u4ee5\u4e0a\u306e\u7c73\u56fd\u306e\u7537\u6027\u533b\u5e2b14,641\u540d\u3092\u5bfe\u8c61\u306b\u3057\u305f\u7814\u7a76\u3067\u3001<a href=\"http:\/\/www.dhcblog.com\/kamohara\/archive\/2344\" class=\"broken_link\" rel=\"nofollow\">\u30de\u30eb\u30c1\u30d3\u30bf\u30df\u30f3\u306b\u3088\u308b\u304c\u3093\u30ea\u30b9\u30af\u4f4e\u6e1b\u52b9\u679c<\/a>\u3068\u3044\u3046\u30c7\u30fc\u30bf\u304c\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u3059\u3002 (\u4eca\u56de\u306e\u30ec\u30d3\u30e5\u30fc\u3067\u3059\u3002) \u307e\u305f\u3001<a href=\"http:\/\/www.dhcblog.com\/kamohara\/archive\/2410\" class=\"broken_link\" rel=\"nofollow\">\u30de\u30eb\u30c1\u30d3\u30bf\u30df\u30f3\u30fb\u30df\u30cd\u30e9\u30eb\u3068\u6b7b\u4ea1\u7387\u306e\u95a2\u4fc2\uff1a\u30e1\u30bf\u89e3\u6790<\/a> \u3068\u3044\u3046\u5831\u544a\u3082\u3042\u308a\u307e\u3059\u3002 \u306a\u304a\u3001\u5065\u5eb7\u5897\u9032\u53ca\u3073\u75be\u75c5\u4e88\u9632\u306b\u306f\u3001\u9069\u5207\u306a\u98df\u7fd2\u6163\u3084\u904b\u52d5\u7fd2\u6163\u304c\u57fa\u672c\u3067\u3042\u308a\u3001\u30b5\u30d7\u30ea\u30e1\u30f3\u30c8\u30fb\u5065\u5eb7\u98df\u54c1\u304c\u305d\u308c\u3089\u306b\u7f6e\u304d\u63db\u308f\u308b\u308f\u3051\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002 \u533b\u7642\u5c02\u9580\u8a8c\u306b\u3088\u308b\u30de\u30eb\u30c1\u30d3\u30bf\u30df\u30f3\u6442\u53d6\u306e\u63a8\u5968\u8ad6\u6587\u3068\u3057\u3066\u306f\u3001\u6b21\u306e2\u3064\u304c\u3088\u304f\u77e5\u3089\u308c\u3066\u3044\u307e\u3059\u3002 \uff08\uff11\uff09NEJM\u8a8c(1998)\u306e\u8ad6\u8aac <a href=\"http:\/\/www.nejm.org\/doi\/full\/10.1056\/NEJM199804093381509\" class=\"broken_link\" rel=\"nofollow\">\u300cEat Right and Take a Multivitamin\u300d<\/a> \u300e\u9069\u5207\u306a\u98df\u4e8b\u3092\u6442\u308a\u3001\u30de\u30eb\u30c1\u30d3\u30bf\u30df\u30f3\u3082\u5229\u7528\u3057\u307e\u3057\u3087\u3046\u300f \uff08\u795e\u7d4c\u7ba1\u6b20\u640d\u75c7\u4e88\u9632\u3001\u52d5\u8108\u786c\u5316\u6027\u75be\u60a3\u4e88\u9632\u306e\u610f\u7fa9\uff09(Oakely GP. NEJM. 1998 Editorial ) \uff08\uff12\uff09JAMA\u8a8c(2002)\u306e\u7dcf\u8aac <a href=\"http:\/\/jama.jamanetwork.com\/article.aspx?articleid=195039\" class=\"broken_link\" rel=\"nofollow\">\u300cVitamins for chronic disease prevention in adults\u300d<\/a> \u300e\u6210\u4eba\u306f\u3001\u6bce\u65e5\u3001\u30de\u30eb\u30c1\u30d3\u30bf\u30df\u30f3\u30b5\u30d7\u30ea\u30e1\u30f3\u30c8\u3092\u6442\u53d6\u3059\u308b\u3079\u304d\u300f\uff08\u5148\u9032\u56fd\u3067\u306f\u6b20\u4e4f\u75c7\u306f\u7a00\u3067\u3042\u308b\u304c\u3001\u81f3\u9069\u6fc3\u5ea6\u3092\u4e0b\u56de\u308b\u3053\u3068\u306e\u30ea\u30b9\u30af\u304c\u3042\u308b\u3002\uff09(Fletcher.et al. JAMA. 2002 )<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u00a0 \u30de\u30eb\u30c1\u30d3\u30bf\u30df\u30f3\u30df\u30cd\u30e9\u30eb\u306f\u304c\u3093\u4e88\u9632\u306b\u5f79\u7acb\u3064\u3068\u3044\u3046\u7814\u7a76\u3067\u3059\u30021993\u5e74\u306b\u306f\u30d3\u30bf\u30df\u30f3\u30df\u30cd\u30e9\u30eb\u306e\u9ad8\u5bb9\u91cf\u6295\u4e0e\u3067\u672b\u671f\u304c\u3093\u60a3\u8005\u304c\u512a\u4f4d\u306b\u4f59\u547d\u304c\u5ef6\u9577\u3057\u305f\u3068\u3044\u3046\u7814\u7a76\u5831\u544a\u3082\u3042\u308a\u307e\u3059\u3002\u8eab\u8fd1\u306b\u3042\u308b\u6804\u990a\u7d20\u3067\u3059\u304c\u3001\u3046\u307e\u304f\u6442\u53d6\u3059\u308c\u3070\u6297\u304c\u3093\u4f5c\u7528\u3001\u304c\u3093 [&hellip;]<\/p>\n","protected":false},"author":6,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[14,3],"tags":[],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/www.taiyou-clinic.jp\/blog\/wp-json\/wp\/v2\/posts\/2062"}],"collection":[{"href":"https:\/\/www.taiyou-clinic.jp\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.taiyou-clinic.jp\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.taiyou-clinic.jp\/blog\/wp-json\/wp\/v2\/users\/6"}],"replies":[{"embeddable":true,"href":"https:\/\/www.taiyou-clinic.jp\/blog\/wp-json\/wp\/v2\/comments?post=2062"}],"version-history":[{"count":1,"href":"https:\/\/www.taiyou-clinic.jp\/blog\/wp-json\/wp\/v2\/posts\/2062\/revisions"}],"predecessor-version":[{"id":2063,"href":"https:\/\/www.taiyou-clinic.jp\/blog\/wp-json\/wp\/v2\/posts\/2062\/revisions\/2063"}],"wp:attachment":[{"href":"https:\/\/www.taiyou-clinic.jp\/blog\/wp-json\/wp\/v2\/media?parent=2062"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.taiyou-clinic.jp\/blog\/wp-json\/wp\/v2\/categories?post=2062"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.taiyou-clinic.jp\/blog\/wp-json\/wp\/v2\/tags?post=2062"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}