{"id":1329,"date":"2013-03-26T10:27:26","date_gmt":"2013-03-26T01:27:26","guid":{"rendered":"https:\/\/www.taiyou-clinic.jp\/blog\/?p=1329"},"modified":"2013-03-26T10:27:26","modified_gmt":"2013-03-26T01:27:26","slug":"%e3%83%8e%e3%82%b3%e3%82%ae%e3%83%aa%e3%83%a4%e3%82%b7%e3%81%a8%e5%89%8d%e7%ab%8b%e8%85%ba%e3%81%8c%e3%82%93%e3%81%ae%e7%82%8e%e7%97%87%e6%8a%91%e5%88%b6%e4%bd%9c%e7%94%a8","status":"publish","type":"post","link":"https:\/\/www.taiyou-clinic.jp\/blog\/archives\/1329","title":{"rendered":"\u30ce\u30b3\u30ae\u30ea\u30e4\u30b7\u3068\u524d\u7acb\u817a\u304c\u3093\u306e\u708e\u75c7\u6291\u5236\u4f5c\u7528"},"content":{"rendered":"

\u30ce\u30b3\u30ae\u30ea\u30e4\u30b7\u306e\u6297\u708e\u75c7\u4f5c\u7528\uff20\u524d\u7acb\u817a\u304c\u3093\u7d30\u80de<\/strong><\/p>\n

\u304c\u3093\u7d30\u80de\u306b\u304a\u3044\u3066\u708e\u75c7\u53cd\u5fdc\u304c\u4f4e\u6e1b\u3059\u308b\u3053\u3068\u306f\u5927\u304d\u306a\u610f\u5473\u3092\u6301\u3064\u3002\u708e\u75c7\u306f\u30ac\u30f3\u3092\u4fc3\u9032\u3059\u308b\u304b\u3089\u3067\u3042\u308b\u3002\u30ce\u30b3\u30ae\u30ea\u30e4\u30b7\u306f\u524d\u7acb\u817a\u304c\u3093\u306e\u9032\u884c\u3092\u6291\u5236\u3059\u308b\u3053\u3068\u304c\u671f\u5f85\u3067\u304d\u308b\u3002<\/p>\n

**************************************<\/p>\n

http:\/\/www.dhcblog.com\/kamohara\/<\/p>\n

\u4eca\u6708\u306e\u708e\u75c7\u7814\u7a76\u306e\u5c02\u9580\u30b8\u30e3\u30fc\u30ca\u30eb\u306b\u3001\u524d\u7acb\u817a\u304c\u3093\u7d30\u80de\u306b\u304a\u3051\u308b\u30ce\u30b3\u30ae\u30ea\u30e4\u30b7\u30a8\u30ad\u30b9\u306e\u6297\u708e\u75c7\u4f5c\u7528\u3092\u793a\u3057\u305f\u57fa\u790e\u7814\u7a76\u304c\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u3057\u305f\u3002(J Inflamm <\/em>(Lond). 2013 Mar 14;10(1):11)<\/p>\n

\u6162\u6027\u708e\u75c7\u306f\u3001\u304c\u3093\u3084\u52d5\u8108\u786c\u5316\u6027\u75be\u60a3\u3001\u80a5\u6e80\u30fb\u30e1\u30bf\u30dc\u30ea\u30c3\u30af\u75c7\u5019\u7fa4\u306a\u3069\u751f\u6d3b\u7fd2\u6163\u75c5\u5168\u822c\u306b\u5171\u901a\u3059\u308b\u75c5\u614b\u3067\u3059\u3002
\n\u304b\u3064\u3066\u3001\u4e00\u822c\u8a8c\u306eTime\u3082\u3001\u2018Inflammation: The Secret Killer\u2019\u3068\u3057\u3066\u30ab\u30d0\u30fc\u7279\u96c6\u3092\u7d44\u3093\u3060\u3053\u3068\u304c\u3042\u308a\u3001\u5e83\u304f\u8a8d\u77e5\u3055\u308c\u3066\u3044\u307e\u3059\u3002
\n\u305d\u3053\u3067\u3001\u30b5\u30d7\u30ea\u30e1\u30f3\u30c8\u7814\u7a76\u3067\u306f\u3001\u6297\u708e\u75c7\u4f5c\u7528\u3092\u6709\u3059\u308b\u6a5f\u80fd\u6027\u98df\u54c1\u6210\u5206\u306e\u50cd\u304d\u304c\u6ce8\u76ee\u3055\u308c\u3066\u3044\u307e\u3059\u3002
\n\u5206\u5b50\u30ec\u30d9\u30eb\u3067\u306f\u3001NF-\u03baB\u7d4c\u8def\u306b\u5bfe\u3059\u308b\u6291\u5236\u4f5c\u7528\u3092\u4ecb\u3057\u305f\u6297\u708e\u75c7\u4f5c\u7528\u304c\u77e5\u3089\u308c\u3066\u3044\u307e\u3059\u3002
\n(\u4f8b\u3048\u3070\u3001\u30a6\u30b3\u30f3\u6210\u5206\u30af\u30eb\u30af\u30df\u30f3\u306b\u3088\u308b\u6297\u708e\u75c7\u4f5c\u7528\u306f\u3001NF-\u03baB\u6291\u5236\u3067\u3059\u3002)<\/p>\n

\u3055\u3066\u3001\u4eca\u56de\u306e\u7814\u7a76\u3067\u306f\u3001\u30ce\u30b3\u30ae\u30ea\u30e4\u30b7\u306b\u3088\u308b\u524d\u7acb\u817a\u304c\u3093\u7d30\u80de\u306b\u304a\u3051\u308b\u708e\u75c7\u60f9\u8d77\u907a\u4f1d\u5b50\u3078\u306e\u5f71\u97ff\u304c\u8abf\u3079\u3089\u308c\u307e\u3057\u305f\u3002
\n\u5177\u4f53\u7684\u306b\u306f\u30012\u7a2e\u985e\u306e\u30d2\u30c8\u524d\u7acb\u817a\u304c\u3093\u7d30\u80de
\n\u3000--\u3000\u30a2\u30f3\u30c9\u30ed\u30b2\u30f3\u4f9d\u5b58\u6027\u524d\u7acb\u817a\u304c\u3093\u7d30\u80de(LNCaP)\u3068\u3001\u30a2\u30f3\u30c9\u30ed\u30b2\u30f3\u975e\u4f9d\u5b58\u6027\u524d\u7acb\u817a\u304c\u3093\u7d30\u80de(PC3)\u3000--\u3000
\n\u3092\u7528\u3044\u3066\u3001\u30ce\u30b3\u30ae\u30ea\u30e4\u30b7\u306b\u3088\u308b\u7d30\u80de\u5897\u6b96\/\u30a2\u30dd\u30c8\u30fc\u30b7\u30b9\u6bd4\u3001\u708e\u75c7\u95a2\u9023\u907a\u4f1d\u5b50\u767a\u73fe\u3001NF-\u03baB\u6d3b\u6027\u5316\u3078\u306e\u4f5c\u7528\u304c\u6e2c\u5b9a\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n

\u708e\u75c7\u95a2\u9023\u907a\u4f1d\u5b50\u3068\u3057\u3066\u306f\u3001IL-6, CCL-5, CCL-2, COX-1, COX-2, iNOS\u306e\u5404\u5206\u5b50\u306e\u907a\u4f1d\u5b50\u767a\u73fe\u304c\u6e2c\u5b9a\u3055\u308c\u307e\u3057\u305f\u3002<\/p>\n

\u307e\u305f\u3001LNCaP \u3068PC3\u306e2\u7a2e\u985e\u306e\u30d2\u30c8\u524d\u7acb\u817a\u304c\u3093\u57f9\u990a\u7d30\u80de\u7cfb\u306b\u52a0\u3048\u3066\u3001
\n\u524d\u7acb\u817a\u304c\u3093\u60a3\u8005\u304b\u3089\u5f97\u3089\u308c\u305f\u300140\u306e\u30d2\u30c8\u524d\u7acb\u817a\u304c\u3093\u521d\u4ee3\u57f9\u990a\u3082\u7528\u3044\u3089\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n

\u3053\u308c\u3089\u306e\u524d\u7acb\u817a\u304c\u3093\u7d30\u80de\u306b\u5bfe\u3057\u3066\u3001\u30ce\u30b3\u30ae\u30ea\u30e4\u30b7\u30a8\u30ad\u30b9(44\u306888 mug\/ml\u306e2\u7a2e\u985e\u306e\u6fc3\u5ea6)\u304c\u3001
\n16, 24, 48, 72\u6642\u9593\u306e\u30bf\u30a4\u30e0\u30b3\u30fc\u30b9\u306b\u3066\u6295\u4e0e\u3055\u308c\u307e\u3057\u305f\u3002<\/p>\n

\u89e3\u6790\u306e\u7d50\u679c\u3001\u30ce\u30b3\u30ae\u30ea\u30e4\u30b7\u30a8\u30ad\u30b9\u6295\u4e0e\u306b\u3088\u3063\u3066\u3001
\n\u524d\u7acb\u817a\u304c\u3093\u7d30\u80de\u304a\u3088\u3073\u6b63\u5e38\u7d30\u80de\u306e\u7d30\u80de\u5897\u6b96\u304a\u3051\u308b\u6709\u610f\u306a\u6291\u5236\u4f5c\u7528\u304c\u898b\u51fa\u3055\u308c\u305f\u3068\u3044\u3046\u3053\u3068\u3067\u3059\u3002
\n(p <0.001)<\/p>\n

\u3053\u306e\u3068\u304d\u3001\u30a2\u30dd\u30c8\u30fc\u30b7\u30b9\u6d3b\u6027\u306e\u6709\u610f\u306a\u4ea2\u9032\u3082\u898b\u51fa\u3055\u308c\u3066\u3044\u307e\u3059\u3002
\n\u307e\u305f\u3001\u708e\u75c7\u95a2\u9023\u907a\u4f1d\u5b50(IL-6, CCL-5, CCL-2, COX-2, iNOS)\u306e\u767a\u73fe\u306f\u3001\u30ce\u30b3\u30ae\u30ea\u30e4\u30b7\u30a8\u30ad\u30b9\u6295\u4e0e\u306b\u3088\u3063\u3066\u3001\u6291\u5236\u3055\u308c\u307e\u3057\u305f\u3002<\/p>\n

\u3055\u3089\u306b\u3001NF-\u03baB\u306ep65\u30b5\u30d6\u30e6\u30cb\u30c3\u30c8\u306e\u6838\u3078\u306e\u79fb\u884c\u304c30\uff05\u4ee5\u4e0a\u6291\u5236\u3055\u308c\u3001NF-\u03baB\u6d3b\u6027\u306e\u963b\u5bb3\u304c\u8a8d\u3081\u3089\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n

\u4ee5\u4e0a\u306e\u30c7\u30fc\u30bf\u304b\u3089\u3001\u30ce\u30b3\u30ae\u30ea\u30e4\u30b7\u30a8\u30ad\u30b9\u6295\u4e0e\u306b\u3088\u3063\u3066\u3001
\n\u524d\u7acb\u817a\u304c\u3093\u7d30\u80de(\u30d2\u30c8\u524d\u7acb\u817a\u304c\u3093\u57f9\u990a\u7d30\u80de\u7cfb\u304a\u3088\u3073\u521d\u4ee3\u57f9\u990a\u7cfb)\u306b\u304a\u3051\u308b\u6297\u708e\u75c7\u4f5c\u7528\u304c\u793a\u5506\u3055\u308c\u307e\u3059\u3002
\n\u4eca\u5f8c\u3001\u81e8\u5e8a\u7684\u610f\u7fa9\u306e\u691c\u8a3c\u304c\u671f\u5f85\u3055\u308c\u307e\u3059\u3002<\/p>\n

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\n\u7537\u6027\u578b\u8131\u6bdb\u75c7(AGA)\u306b\u5bfe\u3059\u308b\u30ce\u30b3\u30ae\u30ea\u30e4\u30b7\u306e\u52b9\u679c<\/a>
\n\u30ce\u30b3\u30ae\u30ea\u30e4\u30b7\u306e\u5b89\u5168\u6027\u3092\u793a\u3057\u305f\u81e8\u5e8a\u8a66\u9a13<\/a>
\n\u30fb\u30ce\u30b3\u30ae\u30ea\u30e4\u30b7\u306b\u3088\u308b\u524d\u7acb\u817a\u80a5\u5927\u75c7\u3068\u52c3\u8d77\u969c\u5bb3\u306e\u75c7\u72b6\u6539\u5584\u4f5c\u7528<\/a>
\n\u30fb\u524d\u7acb\u817a\u306e\u5065\u5eb7\u7dad\u6301\u306b\u306f\u30ce\u30b3\u30ae\u30ea\u30e4\u30b7\uff0b\u30ea\u30b3\u30d4\u30f3\uff0b\u30bb\u30ec\u30f3<\/a>
\n\u30fb\u30ce\u30b3\u30ae\u30ea\u30e4\u30b7\u306b\u3088\u308b\u7d30\u80de\u5897\u6b96\u6291\u5236\u4f5c\u7528<\/a>
\n\u30fb\u30ce\u30b3\u30ae\u30ea\u30e4\u30b7\u306b\u3088\u308bBPH\u75c7\u72b6\u6539\u5584\u4f5c\u7528<\/a>
\n\u30fb\u30ce\u30b3\u30ae\u30ea\u30e4\u30b7\u306e\u524d\u7acb\u817a\u80a5\u5927\u75c7\u6539\u5584\u4f5c\u7528<\/a>
\n\u30fb\u524d\u7acb\u817a\u5207\u9664\u8853\u524d\u306e\u30ce\u30b3\u30ae\u30ea\u30e4\u30b7\u6295\u4e0e\u306e\u52b9\u679c<\/a>
\n\u30fb\u30ce\u30b3\u30ae\u30ea\u30e4\u30b7\u8907\u5408\u30b5\u30d7\u30ea\u306b\u3088\u308b\u6162\u6027\u524d\u7acb\u817a\u708e\u6539\u5584\u52b9\u679c<\/a>
\n\u30fb\u30ce\u30b3\u30ae\u30ea\u30e4\u30b7\u30fb\u30ab\u30dc\u30c1\u30e3\u7a2e\u5b50\u306b\u3088\u308b\u524d\u7acb\u817a\u80a5\u5927\u75c7<\/a>
\n\u30fb\u524d\u7acb\u817a\u5207\u9664\u8853\u306e\u51fa\u8840\u306b\u30ce\u30b3\u30ae\u30ea\u30e4\u30b7\u306f\u5f71\u97ff\u3057\u306a\u3044<\/a>
\n\u30fb\u30ce\u30b3\u30ae\u30ea\u30e4\u30b7\u3067\u306f\u533b\u85ac\u54c1\u3068\u306e\u76f8\u4e92\u4f5c\u7528\u5831\u544a\u306f\u306a\u3057<\/a>
\n\u30fb\u7537\u6027\u578b\u8131\u6bdb\u75c7\u3068\u30ce\u30b3\u30ae\u30ea\u30e4\u30b7<\/a>
\n\u30fb\u30ce\u30b3\u30ae\u30ea\u30e4\u30b7\u306e\u5b89\u5168\u6027\u306b\u95a2\u3059\u308b\u7cfb\u7d71\u7684\u30ec\u30d3\u30e5\u30fc<\/a>
\n\u30fb\u524d\u7acb\u817a\u708e\u306b\u5bfe\u3059\u308b\u88dc\u5b8c\u7642\u6cd5\u3068\u3057\u3066\u306e\u30ce\u30b3\u30ae\u30ea\u30e4\u30b7<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

\u30ce\u30b3\u30ae\u30ea\u30e4\u30b7\u306e\u6297\u708e\u75c7\u4f5c\u7528\uff20\u524d\u7acb\u817a\u304c\u3093\u7d30\u80de \u304c\u3093\u7d30\u80de\u306b\u304a\u3044\u3066\u708e\u75c7\u53cd\u5fdc\u304c\u4f4e\u6e1b\u3059\u308b\u3053\u3068\u306f\u5927\u304d\u306a\u610f\u5473\u3092\u6301\u3064\u3002\u708e\u75c7\u306f\u30ac\u30f3\u3092\u4fc3\u9032\u3059\u308b\u304b\u3089\u3067\u3042\u308b\u3002\u30ce\u30b3\u30ae\u30ea\u30e4\u30b7\u306f\u524d\u7acb\u817a\u304c\u3093\u306e\u9032\u884c\u3092\u6291\u5236\u3059\u308b\u3053\u3068\u304c\u671f\u5f85\u3067\u304d\u308b\u3002 ************** […]<\/p>\n","protected":false},"author":6,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[14],"tags":[],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/www.taiyou-clinic.jp\/blog\/wp-json\/wp\/v2\/posts\/1329"}],"collection":[{"href":"https:\/\/www.taiyou-clinic.jp\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.taiyou-clinic.jp\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.taiyou-clinic.jp\/blog\/wp-json\/wp\/v2\/users\/6"}],"replies":[{"embeddable":true,"href":"https:\/\/www.taiyou-clinic.jp\/blog\/wp-json\/wp\/v2\/comments?post=1329"}],"version-history":[{"count":0,"href":"https:\/\/www.taiyou-clinic.jp\/blog\/wp-json\/wp\/v2\/posts\/1329\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.taiyou-clinic.jp\/blog\/wp-json\/wp\/v2\/media?parent=1329"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.taiyou-clinic.jp\/blog\/wp-json\/wp\/v2\/categories?post=1329"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.taiyou-clinic.jp\/blog\/wp-json\/wp\/v2\/tags?post=1329"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}